5-chloro-N-(5-nitro-1,3-thiazol-2-yl)thiophene-2-carboxamide
TL;DR: 5-chloro-N-(5-nitro-1,3-thiazol-2-yl)thiophene-2-carboxamide (CAS 78682-88-9) is a chemical compound with molecular formula C8H4ClN3O3S2 and molecular weight 288.94 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-chloro-N-(5-nitro-1,3-thiazol-2-yl)thiophene-2-carboxamide
Also Known As: 5-chloro-N-(5-nitro-1,3-thiazol-2-yl)thiophene-2-carboxamide
| Molecular Formula | C8H4ClN3O3S2 |
|---|---|
| Molecular Weight | 288.94 g/mol |
| LogP | 3.9 |
| Topological Polar Surface Area | 144.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 2 |
| Exact Mass | 288.93826 |
| Heavy Atoms | 17 |
| Complexity | 328.0 |
Chemical Identifiers
| CAS Number | 78682-88-9 |
|---|---|
| SMILES | C1=C(SC(=C1)Cl)C(=O)NC2=NC=C(S2)[N+](=O)[O-] |
| InChIKey | GLXJWQYMCKBBGS-UHFFFAOYSA-N |
Product Overview
5-chloro-N-(5-nitro-1,3-thiazol-2-yl)thiophene-2-carboxamide (CAS 78682-88-9), with molecular formula C8H4ClN3O3S2 and molecular weight 288.94 g/mol. IUPAC: 5-chloro-N-(5-nitro-1,3-thiazol-2-yl)thiophene-2-carboxamide.
Chemical Property Profile of 5-chloro-N-(5-nitro-1,3-thiazol-2-yl)thiophene-2-carboxamide
Property Insights of 5-chloro-N-(5-nitro-1,3-thiazol-2-yl)thiophene-2-carboxamide
The XLogP value of 3.9 indicates that 5-chloro-N-(5-nitro-1,3-thiazol-2-yl)thiophene-2-carboxamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 144.0 Ų indicates high polarity, suggesting 5-chloro-N-(5-nitro-1,3-thiazol-2-yl)thiophene-2-carboxamide may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 5-chloro-N-(5-nitro-1,3-thiazol-2-yl)thiophene-2-carboxamide has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-chloro-N-(5-nitro-1,3-thiazol-2-yl)thiophene-2-carboxamide?
The CAS number of 5-chloro-N-(5-nitro-1,3-thiazol-2-yl)thiophene-2-carboxamide is 78682-88-9.
What is the molecular formula of 5-chloro-N-(5-nitro-1,3-thiazol-2-yl)thiophene-2-carboxamide?
The molecular formula of 5-chloro-N-(5-nitro-1,3-thiazol-2-yl)thiophene-2-carboxamide is C8H4ClN3O3S2.
What is the molecular weight of 5-chloro-N-(5-nitro-1,3-thiazol-2-yl)thiophene-2-carboxamide?
The molecular weight of 5-chloro-N-(5-nitro-1,3-thiazol-2-yl)thiophene-2-carboxamide is 288.94 g/mol.
Where can I buy 5-chloro-N-(5-nitro-1,3-thiazol-2-yl)thiophene-2-carboxamide?
You can request a quote for 5-chloro-N-(5-nitro-1,3-thiazol-2-yl)thiophene-2-carboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-chloro-N-(5-nitro-1,3-thiazol-2-yl)thiophene-2-carboxamide?
Yes, KEHONG BIO provides custom synthesis services for 5-chloro-N-(5-nitro-1,3-thiazol-2-yl)thiophene-2-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.