Amorolfine hydrochloride
TL;DR: Amorolfine hydrochloride (CAS 78613-38-4) is a chemical compound with molecular formula C21H36ClNO and molecular weight 353.25 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2R,6S)-2,6-dimethyl-4-[2-methyl-3-[4-(2-methylbutan-2-yl)phenyl]propyl]morpholine;hydrochloride
Also Known As: amorolfine hydrochloride, Amorolfine HCl, Loceryl, amorolfin, Curanail
| Molecular Formula | C21H36ClNO |
|---|---|
| Molecular Weight | 353.25 g/mol |
| LogP | 5.08 |
| Topological Polar Surface Area | 12.5 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 6 |
| Exact Mass | 353.24854 |
| Heavy Atoms | 24 |
| Complexity | 336.0 |
Chemical Identifiers
| CAS Number | 78613-38-4 |
|---|---|
| SMILES | CCC(C)(C)C1=CC=C(C=C1)CC(C)CN2C[C@H](O[C@H](C2)C)C.Cl |
| InChIKey | XZKWIPVTHGWDCF-KUZYQSSXSA-N |
Patent-Derived Application Labels
Derived from 7 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Amorolfine hydrochloride (CAS 78613-38-4), with molecular formula C21H36ClNO and molecular weight 353.25 g/mol. IUPAC: (2R,6S)-2,6-dimethyl-4-[2-methyl-3-[4-(2-methylbutan-2-yl)phenyl]propyl]morpholine;hydrochloride.
Chemical Property Profile of Amorolfine hydrochloride
Property Insights of Amorolfine hydrochloride
The XLogP value of 5.08 indicates that Amorolfine hydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 12.5 Ų, Amorolfine hydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Amorolfine hydrochloride has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Amorolfine hydrochloride?
The CAS number of Amorolfine hydrochloride is 78613-38-4.
What is the molecular formula of Amorolfine hydrochloride?
The molecular formula of Amorolfine hydrochloride is C21H36ClNO.
What is the molecular weight of Amorolfine hydrochloride?
The molecular weight of Amorolfine hydrochloride is 353.25 g/mol.
Where can I buy Amorolfine hydrochloride?
You can request a quote for Amorolfine hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Amorolfine hydrochloride?
Yes, KEHONG BIO provides custom synthesis services for Amorolfine hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.