3beta,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-oic acid structure

3beta,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-oic acid

TL;DR: 3beta,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-oic acid (CAS 78608-74-9) is a chemical compound with molecular formula C27H46O5 and molecular weight 450.33 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(6R)-2-methyl-6-[(3S,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]heptanoic acid

Also Known As: Trihydroxycholestanoic acid, 3beta,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-oic acid, (3, A,5, A,7

CAS: 78608-74-9
Molecular Formula C27H46O5
Molecular Weight 450.33 g/mol
LogP 4.4749
Topological Polar Surface Area 97.99 Ų
Hydrogen Bond Donors 4
Hydrogen Bond Acceptors 4
Rotatable Bonds 6
Exact Mass 450.33453
Heavy Atoms 32
Complexity 695.5342

Chemical Identifiers

CAS Number 78608-74-9
SMILES C[C@H](CCCC(C)C(=O)O)[C@H]1CC[C@@H]2[C@@]1([C@H](C[C@H]3[C@H]2[C@@H](C[C@H]4[C@@]3(CC[C@@H](C4)O)C)O)O)C

Product Overview

3beta,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-oic acid (CAS 78608-74-9), with molecular formula C27H46O5 and molecular weight 450.33 g/mol. IUPAC: (6R)-2-methyl-6-[(3S,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]heptanoic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 3beta,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-oic acid

XLogP
4.4749
TPSA (Topological Polar Surface Area)
97.99
Hydrogen Bond Donors
4
Hydrogen Bond Acceptors
4
Rotatable Bonds
6
Heavy Atoms
32
Complexity
695.5342
Exact Mass
450.33453
Monoisotopic Mass
450.33453
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 3beta,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-oic acid

The XLogP value of 4.4749 indicates that 3beta,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-oic acid is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 97.99 Ų falls within the moderate polarity range, balancing permeability and solubility for 3beta,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-oic acid. Following Lipinski's Rule of Five, 3beta,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-oic acid has 4 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 3beta,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-oic acid?

The CAS number of 3beta,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-oic acid is 78608-74-9.

What is the molecular formula of 3beta,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-oic acid?

The molecular formula of 3beta,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-oic acid is C27H46O5.

What is the molecular weight of 3beta,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-oic acid?

The molecular weight of 3beta,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-oic acid is 450.33 g/mol.

Where can I buy 3beta,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-oic acid?

You can request a quote for 3beta,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-oic acid directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 3beta,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-oic acid?

Yes, KEHONG BIO provides custom synthesis services for 3beta,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-oic acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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