DI-Tert-butylphosphorochloridite structure

DI-Tert-butylphosphorochloridite

TL;DR: DI-Tert-butylphosphorochloridite (CAS 78543-77-8) is a chemical compound with molecular formula C8H18ClO2P and molecular weight 212.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

chloro-bis[(2-methylpropan-2-yl)oxy]phosphane

Also Known As: DI-TERT-BUTYLPHOSPHOROCHLORIDITE, Di-tert-butyl-chlorphosphit, Di-tert-butyl Phosphorochloridite, Chloro-bis[(2-methylpropan-2-yl)oxy]phosphane, bis(1,1-Dimethylethyl) Phosphorochloridous Acid Ester

CAS: 78543-77-8
Molecular Formula C8H18ClO2P
Molecular Weight 212.07 g/mol
LogP 4.0823
Topological Polar Surface Area 18.46 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 2
Rotatable Bonds 2
Exact Mass 212.07329
Heavy Atoms 12
Complexity 120.97374

Chemical Identifiers

CAS Number 78543-77-8
SMILES CC(C)(C)OP(OC(C)(C)C)Cl

Product Overview

DI-Tert-butylphosphorochloridite (CAS 78543-77-8), with molecular formula C8H18ClO2P and molecular weight 212.07 g/mol. IUPAC: chloro-bis[(2-methylpropan-2-yl)oxy]phosphane.

🧪
Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of DI-Tert-butylphosphorochloridite

XLogP
4.0823
TPSA (Topological Polar Surface Area)
18.46
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
2
Rotatable Bonds
2
Heavy Atoms
12
Complexity
120.97374
Exact Mass
212.07329
Monoisotopic Mass
212.07329
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of DI-Tert-butylphosphorochloridite

The XLogP value of 4.0823 indicates that DI-Tert-butylphosphorochloridite is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 18.46 Ų, DI-Tert-butylphosphorochloridite exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, DI-Tert-butylphosphorochloridite has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of DI-Tert-butylphosphorochloridite?

The CAS number of DI-Tert-butylphosphorochloridite is 78543-77-8.

What is the molecular formula of DI-Tert-butylphosphorochloridite?

The molecular formula of DI-Tert-butylphosphorochloridite is C8H18ClO2P.

What is the molecular weight of DI-Tert-butylphosphorochloridite?

The molecular weight of DI-Tert-butylphosphorochloridite is 212.07 g/mol.

Where can I buy DI-Tert-butylphosphorochloridite?

You can request a quote for DI-Tert-butylphosphorochloridite directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for DI-Tert-butylphosphorochloridite?

Yes, KEHONG BIO provides custom synthesis services for DI-Tert-butylphosphorochloridite and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

🤖 科弘生物 AI 助手 ×
您好!我是 科弘生物 AI 助手。可以问我产品搜索、询价、样品或技术问题。如何帮助您?