Locicortolone Dicibate
TL;DR: Locicortolone Dicibate (CAS 78467-68-2) is a chemical compound with molecular formula C36H50Cl2O5 and molecular weight 632.30 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[2-[(8S,9R,10S,11S,13S,14S,16R,17S)-9,11-dichloro-10,13,16-trimethyl-3-oxo-7,8,11,12,14,15,16,17-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] dicyclohexylmethyl carbonate
Also Known As: Locicortolone dicibate, Locicortone, Locicortolone, locicortoloni dicibas, dicibate de locicortolone
| Molecular Formula | C36H50Cl2O5 |
|---|---|
| Molecular Weight | 632.30 g/mol |
| LogP | 8.9867 |
| Topological Polar Surface Area | 69.67 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 632.3035 |
| Heavy Atoms | 43 |
| Complexity | 1150.136 |
Chemical Identifiers
| CAS Number | 78467-68-2 |
|---|---|
| SMILES | C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@H]1C(=O)COC(=O)OC(C5CCCCC5)C6CCCCC6)C)Cl)Cl)C |
Product Overview
Locicortolone Dicibate (CAS 78467-68-2), with molecular formula C36H50Cl2O5 and molecular weight 632.30 g/mol. IUPAC: [2-[(8S,9R,10S,11S,13S,14S,16R,17S)-9,11-dichloro-10,13,16-trimethyl-3-oxo-7,8,11,12,14,15,16,17-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] dicyclohexylmethyl carbonate.
Chemical Property Profile of Locicortolone Dicibate
Property Insights of Locicortolone Dicibate
The XLogP value of 8.9867 indicates that Locicortolone Dicibate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 69.67 Ų falls within the moderate polarity range, balancing permeability and solubility for Locicortolone Dicibate. Following Lipinski's Rule of Five, Locicortolone Dicibate has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Locicortolone Dicibate?
The CAS number of Locicortolone Dicibate is 78467-68-2.
What is the molecular formula of Locicortolone Dicibate?
The molecular formula of Locicortolone Dicibate is C36H50Cl2O5.
What is the molecular weight of Locicortolone Dicibate?
The molecular weight of Locicortolone Dicibate is 632.30 g/mol.
Where can I buy Locicortolone Dicibate?
You can request a quote for Locicortolone Dicibate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Locicortolone Dicibate?
Yes, KEHONG BIO provides custom synthesis services for Locicortolone Dicibate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.