N-(4-(3,4-Difluorophenyl)thiazol-2-yl)-2-(methylthio)nicotinamide
TL;DR: N-(4-(3,4-Difluorophenyl)thiazol-2-yl)-2-(methylthio)nicotinamide (CAS 784159-79-1) is a chemical compound with molecular formula C16H11F2N3OS2 and molecular weight 363.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[4-(3,4-difluorophenyl)-1,3-thiazol-2-yl]-2-methylsulfanylpyridine-3-carboxamide
Also Known As: starbld0002937, AB00726813-01, N-(4-(3,4-Difluorophenyl)thiazol-2-yl)-2-(methylthio)nicotinamide, N-[4-(3,4-difluorophenyl)-1,3-thiazol-2-yl]-2-(methylsulfanyl)pyridine-3-carboxamide, N-[4-(3,4-difluorophenyl)-1,3-thiazol-2-yl]-2-methylsulfanylpyridine-3-carboxamide
| Molecular Formula | C16H11F2N3OS2 |
|---|---|
| Molecular Weight | 363.03 g/mol |
| LogP | 4.4575 |
| Topological Polar Surface Area | 54.88 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 363.03116 |
| Heavy Atoms | 24 |
| Complexity | 898.53394 |
Chemical Identifiers
| CAS Number | 784159-79-1 |
|---|---|
| SMILES | CSC1=C(C=CC=N1)C(=O)NC2=NC(=CS2)C3=CC(=C(C=C3)F)F |
Product Overview
N-(4-(3,4-Difluorophenyl)thiazol-2-yl)-2-(methylthio)nicotinamide (CAS 784159-79-1), with molecular formula C16H11F2N3OS2 and molecular weight 363.03 g/mol. IUPAC: N-[4-(3,4-difluorophenyl)-1,3-thiazol-2-yl]-2-methylsulfanylpyridine-3-carboxamide.
Chemical Property Profile of N-(4-(3,4-Difluorophenyl)thiazol-2-yl)-2-(methylthio)nicotinamide
Property Insights of N-(4-(3,4-Difluorophenyl)thiazol-2-yl)-2-(methylthio)nicotinamide
The XLogP value of 4.4575 indicates that N-(4-(3,4-Difluorophenyl)thiazol-2-yl)-2-(methylthio)nicotinamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 54.88 Ų, N-(4-(3,4-Difluorophenyl)thiazol-2-yl)-2-(methylthio)nicotinamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(4-(3,4-Difluorophenyl)thiazol-2-yl)-2-(methylthio)nicotinamide has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(4-(3,4-Difluorophenyl)thiazol-2-yl)-2-(methylthio)nicotinamide?
The CAS number of N-(4-(3,4-Difluorophenyl)thiazol-2-yl)-2-(methylthio)nicotinamide is 784159-79-1.
What is the molecular formula of N-(4-(3,4-Difluorophenyl)thiazol-2-yl)-2-(methylthio)nicotinamide?
The molecular formula of N-(4-(3,4-Difluorophenyl)thiazol-2-yl)-2-(methylthio)nicotinamide is C16H11F2N3OS2.
What is the molecular weight of N-(4-(3,4-Difluorophenyl)thiazol-2-yl)-2-(methylthio)nicotinamide?
The molecular weight of N-(4-(3,4-Difluorophenyl)thiazol-2-yl)-2-(methylthio)nicotinamide is 363.03 g/mol.
Where can I buy N-(4-(3,4-Difluorophenyl)thiazol-2-yl)-2-(methylthio)nicotinamide?
You can request a quote for N-(4-(3,4-Difluorophenyl)thiazol-2-yl)-2-(methylthio)nicotinamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(4-(3,4-Difluorophenyl)thiazol-2-yl)-2-(methylthio)nicotinamide?
Yes, KEHONG BIO provides custom synthesis services for N-(4-(3,4-Difluorophenyl)thiazol-2-yl)-2-(methylthio)nicotinamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.