N-(2-Amino-4-(trifluoromethyl)phenyl)morpholine
TL;DR: N-(2-Amino-4-(trifluoromethyl)phenyl)morpholine (CAS 784-57-6) is a chemical compound with molecular formula C11H13F3N2O and molecular weight 246.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-morpholin-4-yl-5-(trifluoromethyl)aniline
Also Known As: 2-morpholino-5-(trifluoromethyl)aniline, 2-(morpholin-4-yl)-5-(trifluoromethyl)aniline, 3-amino-4-(4-morpholino)benzotrifluoride, 2-morpholin-4-yl-5-(trifluoromethyl)aniline, 2-(4-morpholinyl)-5-(trifluoromethyl)aniline
| Molecular Formula | C11H13F3N2O |
|---|---|
| Molecular Weight | 246.10 g/mol |
| LogP | 1.9 |
| Topological Polar Surface Area | 38.5 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 1 |
| Exact Mass | 246.09799 |
| Heavy Atoms | 17 |
| Complexity | 254.0 |
| Solubility | 36.7 [ug/mL] (The mean of the results at pH 7.4) |
Chemical Identifiers
| CAS Number | 784-57-6 |
|---|---|
| SMILES | C1COCCN1C2=C(C=C(C=C2)C(F)(F)F)N |
| InChIKey | CNVOJNRNRNAOOP-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 4 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
N-(2-Amino-4-(trifluoromethyl)phenyl)morpholine (CAS 784-57-6), with molecular formula C11H13F3N2O and molecular weight 246.10 g/mol. IUPAC: 2-morpholin-4-yl-5-(trifluoromethyl)aniline.
Chemical Property Profile of N-(2-Amino-4-(trifluoromethyl)phenyl)morpholine
Property Insights of N-(2-Amino-4-(trifluoromethyl)phenyl)morpholine
The XLogP value of 1.9 suggests moderate lipophilicity, balancing water solubility and membrane permeability for N-(2-Amino-4-(trifluoromethyl)phenyl)morpholine. With a topological polar surface area (TPSA) of 38.5 Ų, N-(2-Amino-4-(trifluoromethyl)phenyl)morpholine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(2-Amino-4-(trifluoromethyl)phenyl)morpholine has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(2-Amino-4-(trifluoromethyl)phenyl)morpholine?
The CAS number of N-(2-Amino-4-(trifluoromethyl)phenyl)morpholine is 784-57-6.
What is the molecular formula of N-(2-Amino-4-(trifluoromethyl)phenyl)morpholine?
The molecular formula of N-(2-Amino-4-(trifluoromethyl)phenyl)morpholine is C11H13F3N2O.
What is the molecular weight of N-(2-Amino-4-(trifluoromethyl)phenyl)morpholine?
The molecular weight of N-(2-Amino-4-(trifluoromethyl)phenyl)morpholine is 246.10 g/mol.
Where can I buy N-(2-Amino-4-(trifluoromethyl)phenyl)morpholine?
You can request a quote for N-(2-Amino-4-(trifluoromethyl)phenyl)morpholine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(2-Amino-4-(trifluoromethyl)phenyl)morpholine?
Yes, KEHONG BIO provides custom synthesis services for N-(2-Amino-4-(trifluoromethyl)phenyl)morpholine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.