4-Azidopuromycin
TL;DR: 4-Azidopuromycin (CAS 78308-46-0) is a chemical compound with molecular formula C21H26N10O4 and molecular weight 482.21 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2S)-2-amino-3-(4-azidophenyl)-N-[(2S,3S,4R,5R)-5-[6-(dimethylamino)purin-9-yl]-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]propanamide
Also Known As: 4-Azidopuromycin, p-Azidopuromycin, para-Azidopuromycin, 3'-[(4-azido-l-phenylalanyl)amino]-3'-deoxy-n,n-dimethyladenosine, 6-Dimethylamino-9-(3'-deoxy-3'-(p-azido-L-phenylalanylamino)-beta-D-ribofuranosyl)purine
| Molecular Formula | C21H26N10O4 |
|---|---|
| Molecular Weight | 482.21 g/mol |
| LogP | 1.0 |
| Topological Polar Surface Area | 166.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 11 |
| Rotatable Bonds | 8 |
| Exact Mass | 482.21384 |
| Heavy Atoms | 35 |
| Complexity | 775.0 |
Chemical Identifiers
| CAS Number | 78308-46-0 |
|---|---|
| SMILES | CN(C)C1=NC=NC2=C1N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)CO)NC(=O)[C@H](CC4=CC=C(C=C4)N=[N+]=[N-])N)O |
| InChIKey | CJEWMVCPQUAUKL-YXDKPKCJSA-N |
Product Overview
4-Azidopuromycin (CAS 78308-46-0), with molecular formula C21H26N10O4 and molecular weight 482.21 g/mol. IUPAC: (2S)-2-amino-3-(4-azidophenyl)-N-[(2S,3S,4R,5R)-5-[6-(dimethylamino)purin-9-yl]-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]propanamide.
Chemical Property Profile of 4-Azidopuromycin
Property Insights of 4-Azidopuromycin
The XLogP value of 1.0 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 4-Azidopuromycin. The TPSA of 166.0 Ų indicates high polarity, suggesting 4-Azidopuromycin may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 4-Azidopuromycin has 4 hydrogen bond donor(s) and 11 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-Azidopuromycin?
The CAS number of 4-Azidopuromycin is 78308-46-0.
What is the molecular formula of 4-Azidopuromycin?
The molecular formula of 4-Azidopuromycin is C21H26N10O4.
What is the molecular weight of 4-Azidopuromycin?
The molecular weight of 4-Azidopuromycin is 482.21 g/mol.
Where can I buy 4-Azidopuromycin?
You can request a quote for 4-Azidopuromycin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-Azidopuromycin?
Yes, KEHONG BIO provides custom synthesis services for 4-Azidopuromycin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.