7-Methylcamptothecin
TL;DR: 7-Methylcamptothecin (CAS 78287-26-0) is a chemical compound with molecular formula C21H18N2O4 and molecular weight 362.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(19S)-19-ethyl-19-hydroxy-10-methyl-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione
Also Known As: 7-Methyl Camptothecin, 7-Methylcamptothecin, 7-Methyl-20(S)-camptothecin, (S)-4-Ethyl-4-hydroxy-11-methyl-1,12-dihydro-14H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H)-dione, (19S)-19-ethyl-19-hydroxy-10-methyl-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione
| Molecular Formula | C21H18N2O4 |
|---|---|
| Molecular Weight | 362.13 g/mol |
| LogP | 2.38802 |
| Topological Polar Surface Area | 81.42 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 1 |
| Exact Mass | 362.12665 |
| Heavy Atoms | 27 |
| Complexity | 1211.0077 |
Chemical Identifiers
| CAS Number | 78287-26-0 |
|---|---|
| SMILES | CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C(C5=CC=CC=C5N=C4C3=C2)C)O |
Product Overview
7-Methylcamptothecin (CAS 78287-26-0), with molecular formula C21H18N2O4 and molecular weight 362.13 g/mol. IUPAC: (19S)-19-ethyl-19-hydroxy-10-methyl-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione.
Chemical Property Profile of 7-Methylcamptothecin
Property Insights of 7-Methylcamptothecin
The XLogP value of 2.38802 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 7-Methylcamptothecin. The TPSA of 81.42 Ų falls within the moderate polarity range, balancing permeability and solubility for 7-Methylcamptothecin. Following Lipinski's Rule of Five, 7-Methylcamptothecin has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 7-Methylcamptothecin?
The CAS number of 7-Methylcamptothecin is 78287-26-0.
What is the molecular formula of 7-Methylcamptothecin?
The molecular formula of 7-Methylcamptothecin is C21H18N2O4.
What is the molecular weight of 7-Methylcamptothecin?
The molecular weight of 7-Methylcamptothecin is 362.13 g/mol.
Where can I buy 7-Methylcamptothecin?
You can request a quote for 7-Methylcamptothecin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 7-Methylcamptothecin?
Yes, KEHONG BIO provides custom synthesis services for 7-Methylcamptothecin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.