Paroxetine Hydrochloride
TL;DR: Paroxetine Hydrochloride (CAS 78246-49-8) is a chemical compound with molecular formula C19H21ClFNO3 and molecular weight 365.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(3S,4R)-3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)piperidine;hydrochloride
Also Known As: Paroxetine hydrochloride, Paroxetine Hcl, Paroxat, Paxil, Seroxat
| Molecular Formula | C19H21ClFNO3 |
|---|---|
| Molecular Weight | 365.12 g/mol |
| LogP | 3.75 |
| Topological Polar Surface Area | 39.7 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 365.1194 |
| Heavy Atoms | 25 |
| Complexity | 402.0 |
Chemical Identifiers
| CAS Number | 78246-49-8 |
|---|---|
| SMILES | C1CNC[C@H]([C@@H]1C2=CC=C(C=C2)F)COC3=CC4=C(C=C3)OCO4.Cl |
| InChIKey | GELRVIPPMNMYGS-RVXRQPKJSA-N |
Patent-Derived Application Labels
Derived from 13 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Paroxetine Hydrochloride (CAS 78246-49-8), with molecular formula C19H21ClFNO3 and molecular weight 365.12 g/mol. IUPAC: (3S,4R)-3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)piperidine;hydrochloride.
Chemical Property Profile of Paroxetine Hydrochloride
Property Insights of Paroxetine Hydrochloride
The XLogP value of 3.75 indicates that Paroxetine Hydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 39.7 Ų, Paroxetine Hydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Paroxetine Hydrochloride has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Paroxetine Hydrochloride?
The CAS number of Paroxetine Hydrochloride is 78246-49-8.
What is the molecular formula of Paroxetine Hydrochloride?
The molecular formula of Paroxetine Hydrochloride is C19H21ClFNO3.
What is the molecular weight of Paroxetine Hydrochloride?
The molecular weight of Paroxetine Hydrochloride is 365.12 g/mol.
Where can I buy Paroxetine Hydrochloride?
You can request a quote for Paroxetine Hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Paroxetine Hydrochloride?
Yes, KEHONG BIO provides custom synthesis services for Paroxetine Hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.