Esaft structure

Esaft

TL;DR: Esaft (CAS 78232-36-7) is a chemical compound with molecular formula C49H53N3O9S and molecular weight 859.35 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

[(8R,9S,13S,14S,17S)-3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] 4-[6-[(3',6'-dihydroxy-3-oxospiro[2-benzofuran-1,9'-xanthene]-5-yl)carbamothioylamino]hexylamino]-4-oxobutanoate

Also Known As: ESAFT, N-(Estradiol-17beta-succinylaminohexyl)-N'-fluoresceinyl-thiourea, [(8R,9S,13S,14S,17S)-3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] 4-[6-[(3',6'-dihydroxy-3-oxospiro[2-benzofuran-1,9'-xanthene]-5-yl)carbamothioylamino]hexylamino]-4-oxobutanoate, Estra-1,3,5(10)-triene-3,17-diol (17beta)-, 17-(4-((6-((((3',6'-dihydroxy-3-oxospiro(isobenzofuran-1(3H),9'-(9H)xanthen)-5-yl)amino)thioxomethyl)amino)hexyl)amino)-4-oxobutanoate), N-[6-({[(3',6'-Dihydroxy-3-oxo-3H-spiro[[2]benzofuran-1,9'-xanthen]-5-yl)amino](sulfanyl)methylidene}amino)hexyl]-4-{[3-hydroxyestra-1(10),2,4-trien-17beta-yl]oxy}-4-oxobutanimidic acid

CAS: 78232-36-7
Molecular Formula C49H53N3O9S
Molecular Weight 859.35 g/mol
LogP 8.5827
Topological Polar Surface Area 175.68 Ų
Hydrogen Bond Donors 6
Hydrogen Bond Acceptors 10
Rotatable Bonds 12
Exact Mass 859.3503
Heavy Atoms 62
Complexity 2385.913

Chemical Identifiers

CAS Number 78232-36-7
SMILES C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2OC(=O)CCC(=O)NCCCCCCNC(=S)NC4=CC5=C(C=C4)C6(C7=C(C=C(C=C7)O)OC8=C6C=CC(=C8)O)OC5=O)CCC9=C3C=CC(=C9)O

Product Overview

Esaft (CAS 78232-36-7), with molecular formula C49H53N3O9S and molecular weight 859.35 g/mol. IUPAC: [(8R,9S,13S,14S,17S)-3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] 4-[6-[(3',6'-dihydroxy-3-oxospiro[2-benzofuran-1,9'-xanthene]-5-yl)carbamothioylamino]hexylamino]-4-oxobutanoate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Esaft

XLogP
8.5827
TPSA (Topological Polar Surface Area)
175.68
Hydrogen Bond Donors
6
Hydrogen Bond Acceptors
10
Rotatable Bonds
12
Heavy Atoms
62
Complexity
2385.913
Exact Mass
859.3503
Monoisotopic Mass
859.3503
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Esaft

The XLogP value of 8.5827 indicates that Esaft is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 175.68 Ų indicates high polarity, suggesting Esaft may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Esaft has 6 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Esaft?

The CAS number of Esaft is 78232-36-7.

What is the molecular formula of Esaft?

The molecular formula of Esaft is C49H53N3O9S.

What is the molecular weight of Esaft?

The molecular weight of Esaft is 859.35 g/mol.

Where can I buy Esaft?

You can request a quote for Esaft directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Esaft?

Yes, KEHONG BIO provides custom synthesis services for Esaft and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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