4-Fluorobenzoyl isothiocyanate structure

4-Fluorobenzoyl isothiocyanate

TL;DR: 4-Fluorobenzoyl isothiocyanate (CAS 78225-74-8) is a chemical compound with molecular formula C8H4FNOS and molecular weight 181.00 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

4-fluorobenzoyl isothiocyanate

Also Known As: 4-fluorobenzoyl isothiocyanate, p-fluorobenzoyl isocyanate, 4-fluorobenzoylisothiocyanate, Benzoyl isothiocyanate, 4-fluoro-, 4-Fluoro-1-benzenecarbonyl isothiocyanate

CAS: 78225-74-8
Molecular Formula C8H4FNOS
Molecular Weight 181.00 g/mol
LogP 3.3
Topological Polar Surface Area 61.5 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 3
Rotatable Bonds 1
Exact Mass 180.99976
Heavy Atoms 12
Complexity 217.0

Chemical Identifiers

CAS Number 78225-74-8
SMILES C1=CC(=CC=C1C(=O)N=C=S)F
InChIKey GZMSWUYBYCVYKI-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 3 IPC patent classification(s) across the SureChEMBL global patent database.

Agrochemicals (2 patents) Heterocyclic Building Blocks (24 patents) Pharmaceutical Intermediates (17 patents)

Product Overview

4-Fluorobenzoyl isothiocyanate (CAS 78225-74-8), with molecular formula C8H4FNOS and molecular weight 181.00 g/mol. IUPAC: 4-fluorobenzoyl isothiocyanate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 4-Fluorobenzoyl isothiocyanate

XLogP
3.3
TPSA (Topological Polar Surface Area)
61.5
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
3
Rotatable Bonds
1
Heavy Atoms
12
Complexity
217.0
Exact Mass
180.99976
Monoisotopic Mass
180.99976
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 4-Fluorobenzoyl isothiocyanate

The XLogP value of 3.3 indicates that 4-Fluorobenzoyl isothiocyanate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 61.5 Ų falls within the moderate polarity range, balancing permeability and solubility for 4-Fluorobenzoyl isothiocyanate. Following Lipinski's Rule of Five, 4-Fluorobenzoyl isothiocyanate has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 4-Fluorobenzoyl isothiocyanate?

The CAS number of 4-Fluorobenzoyl isothiocyanate is 78225-74-8.

What is the molecular formula of 4-Fluorobenzoyl isothiocyanate?

The molecular formula of 4-Fluorobenzoyl isothiocyanate is C8H4FNOS.

What is the molecular weight of 4-Fluorobenzoyl isothiocyanate?

The molecular weight of 4-Fluorobenzoyl isothiocyanate is 181.00 g/mol.

Where can I buy 4-Fluorobenzoyl isothiocyanate?

You can request a quote for 4-Fluorobenzoyl isothiocyanate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 4-Fluorobenzoyl isothiocyanate?

Yes, KEHONG BIO provides custom synthesis services for 4-Fluorobenzoyl isothiocyanate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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