Phosphoric triamide, N,N-bis(2-chloroethyl)-N',N',N'',N''-tetramethyl structure

Phosphoric triamide, N,N-bis(2-chloroethyl)-N',N',N'',N''-tetramethyl

TL;DR: Phosphoric triamide, N,N-bis(2-chloroethyl)-N',N',N'',N''-tetramethyl (CAS 78218-74-3) is a chemical compound with molecular formula C8H20Cl2N3OP and molecular weight 275.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

N-[bis(dimethylamino)phosphoryl]-2-chloro-N-(2-chloroethyl)ethanamine

Also Known As: Cyclophosphamide Impurity 46, B 495, Phosphoric triamide, N,N-bis(2-chloroethyl)-N',N',N'',N''-tetramethyl, B-495, N,N-Bis(2-chloroethyl) N',N',N'',N''-tetramethyl phosphorotriamide

CAS: 78218-74-3
Molecular Formula C8H20Cl2N3OP
Molecular Weight 275.07 g/mol
LogP 1.9973
Topological Polar Surface Area 26.79 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 1
Rotatable Bonds 7
Exact Mass 275.0721
Heavy Atoms 15
Complexity 207.93233

Chemical Identifiers

CAS Number 78218-74-3
SMILES CN(C)P(=O)(N(C)C)N(CCCl)CCCl

Product Overview

Phosphoric triamide, N,N-bis(2-chloroethyl)-N',N',N'',N''-tetramethyl (CAS 78218-74-3), with molecular formula C8H20Cl2N3OP and molecular weight 275.07 g/mol. IUPAC: N-[bis(dimethylamino)phosphoryl]-2-chloro-N-(2-chloroethyl)ethanamine.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of Phosphoric triamide, N,N-bis(2-chloroethyl)-N',N',N'',N''-tetramethyl

XLogP
1.9973
TPSA (Topological Polar Surface Area)
26.79
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
1
Rotatable Bonds
7
Heavy Atoms
15
Complexity
207.93233
Exact Mass
275.0721
Monoisotopic Mass
275.0721
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Phosphoric triamide, N,N-bis(2-chloroethyl)-N',N',N'',N''-tetramethyl

The XLogP value of 1.9973 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Phosphoric triamide, N,N-bis(2-chloroethyl)-N',N',N'',N''-tetramethyl. With a topological polar surface area (TPSA) of 26.79 Ų, Phosphoric triamide, N,N-bis(2-chloroethyl)-N',N',N'',N''-tetramethyl exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Phosphoric triamide, N,N-bis(2-chloroethyl)-N',N',N'',N''-tetramethyl has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Phosphoric triamide, N,N-bis(2-chloroethyl)-N',N',N'',N''-tetramethyl?

The CAS number of Phosphoric triamide, N,N-bis(2-chloroethyl)-N',N',N'',N''-tetramethyl is 78218-74-3.

What is the molecular formula of Phosphoric triamide, N,N-bis(2-chloroethyl)-N',N',N'',N''-tetramethyl?

The molecular formula of Phosphoric triamide, N,N-bis(2-chloroethyl)-N',N',N'',N''-tetramethyl is C8H20Cl2N3OP.

What is the molecular weight of Phosphoric triamide, N,N-bis(2-chloroethyl)-N',N',N'',N''-tetramethyl?

The molecular weight of Phosphoric triamide, N,N-bis(2-chloroethyl)-N',N',N'',N''-tetramethyl is 275.07 g/mol.

Where can I buy Phosphoric triamide, N,N-bis(2-chloroethyl)-N',N',N'',N''-tetramethyl?

You can request a quote for Phosphoric triamide, N,N-bis(2-chloroethyl)-N',N',N'',N''-tetramethyl directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Phosphoric triamide, N,N-bis(2-chloroethyl)-N',N',N'',N''-tetramethyl?

Yes, KEHONG BIO provides custom synthesis services for Phosphoric triamide, N,N-bis(2-chloroethyl)-N',N',N'',N''-tetramethyl and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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