![4-[4-(2-Thiophen-2-ylquinazolin-4-yl)piperazin-1-yl]phenol structure](/static/products/7816/781628-91-9.webp)
4-[4-(2-Thiophen-2-ylquinazolin-4-yl)piperazin-1-yl]phenol
TL;DR: 4-[4-(2-Thiophen-2-ylquinazolin-4-yl)piperazin-1-yl]phenol (CAS 781628-91-9) is a chemical compound with molecular formula C22H20N4OS and molecular weight 388.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-[4-(2-thiophen-2-ylquinazolin-4-yl)piperazin-1-yl]phenol
Also Known As: 4-[4-(2-thiophen-2-ylquinazolin-4-yl)piperazin-1-yl]phenol, 4-[4-[2-(2-thienyl)quinazolin-4-yl]piperazino]phenol, 4-[4-(2-thiophen-2-yl-4-quinazolinyl)-1-piperazinyl]phenol, 4-{4-[2-(THIOPHEN-2-YL)QUINAZOLIN-4-YL]PIPERAZIN-1-YL}PHENOL
| Molecular Formula | C22H20N4OS |
|---|---|
| Molecular Weight | 388.14 g/mol |
| LogP | 4.3905 |
| Topological Polar Surface Area | 52.49 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 3 |
| Exact Mass | 388.13577 |
| Heavy Atoms | 28 |
| Complexity | 1087.4427 |
Chemical Identifiers
| CAS Number | 781628-91-9 |
|---|---|
| SMILES | C1CN(CCN1C2=CC=C(C=C2)O)C3=NC(=NC4=CC=CC=C43)C5=CC=CS5 |
Product Overview
4-[4-(2-Thiophen-2-ylquinazolin-4-yl)piperazin-1-yl]phenol (CAS 781628-91-9), with molecular formula C22H20N4OS and molecular weight 388.14 g/mol. IUPAC: 4-[4-(2-thiophen-2-ylquinazolin-4-yl)piperazin-1-yl]phenol.
Chemical Property Profile of 4-[4-(2-Thiophen-2-ylquinazolin-4-yl)piperazin-1-yl]phenol
Property Insights of 4-[4-(2-Thiophen-2-ylquinazolin-4-yl)piperazin-1-yl]phenol
The XLogP value of 4.3905 indicates that 4-[4-(2-Thiophen-2-ylquinazolin-4-yl)piperazin-1-yl]phenol is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 52.49 Ų, 4-[4-(2-Thiophen-2-ylquinazolin-4-yl)piperazin-1-yl]phenol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-[4-(2-Thiophen-2-ylquinazolin-4-yl)piperazin-1-yl]phenol has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-[4-(2-Thiophen-2-ylquinazolin-4-yl)piperazin-1-yl]phenol?
The CAS number of 4-[4-(2-Thiophen-2-ylquinazolin-4-yl)piperazin-1-yl]phenol is 781628-91-9.
What is the molecular formula of 4-[4-(2-Thiophen-2-ylquinazolin-4-yl)piperazin-1-yl]phenol?
The molecular formula of 4-[4-(2-Thiophen-2-ylquinazolin-4-yl)piperazin-1-yl]phenol is C22H20N4OS.
What is the molecular weight of 4-[4-(2-Thiophen-2-ylquinazolin-4-yl)piperazin-1-yl]phenol?
The molecular weight of 4-[4-(2-Thiophen-2-ylquinazolin-4-yl)piperazin-1-yl]phenol is 388.14 g/mol.
Where can I buy 4-[4-(2-Thiophen-2-ylquinazolin-4-yl)piperazin-1-yl]phenol?
You can request a quote for 4-[4-(2-Thiophen-2-ylquinazolin-4-yl)piperazin-1-yl]phenol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-[4-(2-Thiophen-2-ylquinazolin-4-yl)piperazin-1-yl]phenol?
Yes, KEHONG BIO provides custom synthesis services for 4-[4-(2-Thiophen-2-ylquinazolin-4-yl)piperazin-1-yl]phenol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.