RefChem:267724 structure

RefChem:267724

TL;DR: RefChem:267724 (CAS 78149-83-4) is a chemical compound with molecular formula C8H17Cl2N2O2P and molecular weight 274.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

N-(2-chloroethyl)-N-(2-chloropropyl)-2-oxo-1,3,2λ5-oxazaphosphinan-2-amine

Also Known As: Cyclophosphamide Impurity 17, B 691, B-691, Tetrahydro-2-(N-(2-chloroethyl)-N-(2-chloropropyl)amino)-2H-1,3,2-oxazaphosphorine 2-oxide, 2H-1,3,2-Oxazaphosphorin-2-amine, N-(2-chloroethyl)-N-(2-chloropropyl)tetrahydro-, 2-oxide

CAS: 78149-83-4
Molecular Formula C8H17Cl2N2O2P
Molecular Weight 274.04 g/mol
LogP 1.1
Topological Polar Surface Area 41.6 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 4
Rotatable Bonds 5
Exact Mass 274.04047
Heavy Atoms 15
Complexity 243.0

Chemical Identifiers

CAS Number 78149-83-4
SMILES CC(CN(CCCl)P1(=O)NCCCO1)Cl
InChIKey SMERYMOESUHYBH-UHFFFAOYSA-N

Product Overview

RefChem:267724 (CAS 78149-83-4), with molecular formula C8H17Cl2N2O2P and molecular weight 274.04 g/mol. IUPAC: N-(2-chloroethyl)-N-(2-chloropropyl)-2-oxo-1,3,2λ5-oxazaphosphinan-2-amine.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of RefChem:267724

XLogP
1.1
TPSA (Topological Polar Surface Area)
41.6
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
4
Rotatable Bonds
5
Heavy Atoms
15
Complexity
243.0
Exact Mass
274.04047
Monoisotopic Mass
274.04047
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of RefChem:267724

The XLogP value of 1.1 suggests moderate lipophilicity, balancing water solubility and membrane permeability for RefChem:267724. With a topological polar surface area (TPSA) of 41.6 Ų, RefChem:267724 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, RefChem:267724 has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of RefChem:267724?

The CAS number of RefChem:267724 is 78149-83-4.

What is the molecular formula of RefChem:267724?

The molecular formula of RefChem:267724 is C8H17Cl2N2O2P.

What is the molecular weight of RefChem:267724?

The molecular weight of RefChem:267724 is 274.04 g/mol.

Where can I buy RefChem:267724?

You can request a quote for RefChem:267724 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for RefChem:267724?

Yes, KEHONG BIO provides custom synthesis services for RefChem:267724 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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