5-Fluorouracil tromethamine
TL;DR: 5-Fluorouracil tromethamine (CAS 78144-69-1) is a chemical compound with molecular formula C8H14FN3O5 and molecular weight 251.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-amino-2-(hydroxymethyl)propane-1,3-diol;5-fluoro-1H-pyrimidine-2,4-dione
Also Known As: 5-Futro, 5-Fluorouracil tromethamine, 5-Fluorouracil tris salt, 2-amino-2-(hydroxymethyl)propane-1,3-diol; 5-fluoro-1H-pyrimidine-2,4-dione, 2,4(1H,3H)-Pyrimidinedione, 5-fluoro-, compd. with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1)
| Molecular Formula | C8H14FN3O5 |
|---|---|
| Molecular Weight | 251.09 g/mol |
| LogP | -3.1369 |
| Topological Polar Surface Area | 145.0 Ų |
| Hydrogen Bond Donors | 6 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 3 |
| Exact Mass | 251.09175 |
| Heavy Atoms | 17 |
| Complexity | 253.0 |
Chemical Identifiers
| CAS Number | 78144-69-1 |
|---|---|
| SMILES | C1=C(C(=O)NC(=O)N1)F.C(C(CO)(CO)N)O |
| InChIKey | UTTUAALGDKCAGB-UHFFFAOYSA-N |
Product Overview
5-Fluorouracil tromethamine (CAS 78144-69-1), with molecular formula C8H14FN3O5 and molecular weight 251.09 g/mol. IUPAC: 2-amino-2-(hydroxymethyl)propane-1,3-diol;5-fluoro-1H-pyrimidine-2,4-dione.
Chemical Property Profile of 5-Fluorouracil tromethamine
Property Insights of 5-Fluorouracil tromethamine
The XLogP value of -3.1369 indicates that 5-Fluorouracil tromethamine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 145.0 Ų indicates high polarity, suggesting 5-Fluorouracil tromethamine may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 5-Fluorouracil tromethamine has 6 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-Fluorouracil tromethamine?
The CAS number of 5-Fluorouracil tromethamine is 78144-69-1.
What is the molecular formula of 5-Fluorouracil tromethamine?
The molecular formula of 5-Fluorouracil tromethamine is C8H14FN3O5.
What is the molecular weight of 5-Fluorouracil tromethamine?
The molecular weight of 5-Fluorouracil tromethamine is 251.09 g/mol.
Where can I buy 5-Fluorouracil tromethamine?
You can request a quote for 5-Fluorouracil tromethamine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-Fluorouracil tromethamine?
Yes, KEHONG BIO provides custom synthesis services for 5-Fluorouracil tromethamine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.