N-Fructosylamphotericin B
TL;DR: N-Fructosylamphotericin B (CAS 78107-92-3) is a chemical compound with molecular formula C53H83NO22 and molecular weight 1085.54 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-[(2R,3S,4S,5S,6R)-3,5-dihydroxy-6-methyl-4-[[(3S,4R,5R)-3,4,5,6-tetrahydroxy-2-oxohexyl]amino]oxan-2-yl]oxy-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid
Also Known As: N-Fructosylamphotericin B, N-Fructosyl-amphotericin B, Amphotericin B, N-D-fructosyl-, (1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-[(2R,3S,4S,5S,6R)-3,5-dihydroxy-6-methyl-4-[[(3S,4R,5R)-3,4,5,6-tetrahydroxy-2-oxohexyl]amino]oxan-2-yl]oxy-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid, (1S,3R,4E,6E,8E,10E,12E,14E,16E,18S,19R,20R,21S,25R,27R,30R,31R,33S,35R,37S,38R)-3-[(2R,3S,4S,5S,6R)-3,5-dihydroxy-6-methyl-4-[[(3S,4R,5R)-3,4,5,6-tetrahydroxy-2-oxohexyl]amino]oxan-2-yl]oxy-19,25,27,30,31,33,35,37-octahydroxy-18,20,21-trimethyl-23-oxo-22,39-dioxabicyclo[33.3.1]nonatriaconta-4,6,8,10,12,14,16-heptaene-38-carboxylic acid
| Molecular Formula | C53H83NO22 |
|---|---|
| Molecular Weight | 1085.54 g/mol |
| LogP | -2.0133 |
| Topological Polar Surface Area | 403.61 Ų |
| Hydrogen Bond Donors | 16 |
| Hydrogen Bond Acceptors | 22 |
| Rotatable Bonds | 10 |
| Exact Mass | 1085.5406 |
| Heavy Atoms | 76 |
| Complexity | 1978.016 |
Chemical Identifiers
| CAS Number | 78107-92-3 |
|---|---|
| SMILES | C[C@H]1/C=C/C=C/C=C/C=C/C=C/C=C/C=C/[C@@H](C[C@H]2[C@@H]([C@H](C[C@](O2)(C[C@H](C[C@H]([C@@H](CC[C@H](C[C@H](CC(=O)O[C@H]([C@@H]([C@@H]1O)C)C)O)O)O)O)O)O)O)C(=O)O)O[C@H]3[C@H]([C@H]([C@@H]([C@H](O3)C)O)NCC(=O)[C@H]([C@@H]([C@@H](CO)O)O)O)O |
Product Overview
N-Fructosylamphotericin B (CAS 78107-92-3), with molecular formula C53H83NO22 and molecular weight 1085.54 g/mol. IUPAC: (1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-[(2R,3S,4S,5S,6R)-3,5-dihydroxy-6-methyl-4-[[(3S,4R,5R)-3,4,5,6-tetrahydroxy-2-oxohexyl]amino]oxan-2-yl]oxy-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid.
Chemical Property Profile of N-Fructosylamphotericin B
Property Insights of N-Fructosylamphotericin B
The XLogP value of -2.0133 indicates that N-Fructosylamphotericin B is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 403.61 Ų indicates high polarity, suggesting N-Fructosylamphotericin B may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, N-Fructosylamphotericin B has 16 hydrogen bond donor(s) and 22 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-Fructosylamphotericin B?
The CAS number of N-Fructosylamphotericin B is 78107-92-3.
What is the molecular formula of N-Fructosylamphotericin B?
The molecular formula of N-Fructosylamphotericin B is C53H83NO22.
What is the molecular weight of N-Fructosylamphotericin B?
The molecular weight of N-Fructosylamphotericin B is 1085.54 g/mol.
Where can I buy N-Fructosylamphotericin B?
You can request a quote for N-Fructosylamphotericin B directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-Fructosylamphotericin B?
Yes, KEHONG BIO provides custom synthesis services for N-Fructosylamphotericin B and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.