cortisol-4-ara-C structure

cortisol-4-ara-C

TL;DR: cortisol-4-ara-C (CAS 78066-05-4) is a chemical compound with molecular formula C30H42N3O12P and molecular weight 667.25 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

[5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl [2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl] hydrogen phosphate

Also Known As: Cortisol-p-ara-C, Cortisol-4-ara-C, 4-amino-1-(5-o-{[(11,17-dihydroxy-3,20-dioxopregn-4-en-21-yl)oxy](hydroxy)phosphoryl}pentofuranosyl)pyrimidin-2(1h)-one, [5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl [2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl] hydrogen phosphate, [5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl [2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] hydrogen phosphate

CAS: 78066-05-4
Molecular Formula C30H42N3O12P
Molecular Weight 667.25 g/mol
LogP -1.5
Topological Polar Surface Area 239.0 Ų
Hydrogen Bond Donors 6
Hydrogen Bond Acceptors 12
Rotatable Bonds 8
Exact Mass 667.2506
Heavy Atoms 46
Complexity 1450.0

Chemical Identifiers

CAS Number 78066-05-4
SMILES CC12CCC(=O)C=C1CCC3C2C(CC4(C3CCC4(C(=O)COP(=O)(O)OCC5C(C(C(O5)N6C=CC(=NC6=O)N)O)O)O)C)O
InChIKey PYRHNBFJHWMQSW-UHFFFAOYSA-N

Product Overview

cortisol-4-ara-C (CAS 78066-05-4), with molecular formula C30H42N3O12P and molecular weight 667.25 g/mol. IUPAC: [5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl [2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl] hydrogen phosphate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of cortisol-4-ara-C

XLogP
-1.5
TPSA (Topological Polar Surface Area)
239.0
Hydrogen Bond Donors
6
Hydrogen Bond Acceptors
12
Rotatable Bonds
8
Heavy Atoms
46
Complexity
1450.0
Exact Mass
667.2506
Monoisotopic Mass
667.2506
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of cortisol-4-ara-C

The XLogP value of -1.5 indicates that cortisol-4-ara-C is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 239.0 Ų indicates high polarity, suggesting cortisol-4-ara-C may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, cortisol-4-ara-C has 6 hydrogen bond donor(s) and 12 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of cortisol-4-ara-C?

The CAS number of cortisol-4-ara-C is 78066-05-4.

What is the molecular formula of cortisol-4-ara-C?

The molecular formula of cortisol-4-ara-C is C30H42N3O12P.

What is the molecular weight of cortisol-4-ara-C?

The molecular weight of cortisol-4-ara-C is 667.25 g/mol.

Where can I buy cortisol-4-ara-C?

You can request a quote for cortisol-4-ara-C directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for cortisol-4-ara-C?

Yes, KEHONG BIO provides custom synthesis services for cortisol-4-ara-C and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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