O-Methylguanosine
TL;DR: O-Methylguanosine (CAS 7803-88-5) is a chemical compound with molecular formula C11H15N5O5 and molecular weight 297.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2R,3R,4S,5R)-2-(2-amino-6-methoxypurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
Also Known As: 6-O-Methyl Guanosine, O-Methylguanosine, o6-methylguanosine, Nelarabine, 6'-O-Methylguanosine
| Molecular Formula | C11H15N5O5 |
|---|---|
| Molecular Weight | 297.11 g/mol |
| LogP | -0.7 |
| Topological Polar Surface Area | 149.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 3 |
| Exact Mass | 297.10733 |
| Heavy Atoms | 21 |
| Complexity | 377.0 |
Chemical Identifiers
| CAS Number | 7803-88-5 |
|---|---|
| SMILES | COC1=NC(=NC2=C1N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)N |
| InChIKey | IXOXBSCIXZEQEQ-KQYNXXCUSA-N |
Patent-Derived Application Labels
Derived from 4 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
O-Methylguanosine (CAS 7803-88-5), with molecular formula C11H15N5O5 and molecular weight 297.11 g/mol. IUPAC: (2R,3R,4S,5R)-2-(2-amino-6-methoxypurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol.
Chemical Property Profile of O-Methylguanosine
Property Insights of O-Methylguanosine
The XLogP value of -0.7 indicates that O-Methylguanosine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 149.0 Ų indicates high polarity, suggesting O-Methylguanosine may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, O-Methylguanosine has 4 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of O-Methylguanosine?
The CAS number of O-Methylguanosine is 7803-88-5.
What is the molecular formula of O-Methylguanosine?
The molecular formula of O-Methylguanosine is C11H15N5O5.
What is the molecular weight of O-Methylguanosine?
The molecular weight of O-Methylguanosine is 297.11 g/mol.
Where can I buy O-Methylguanosine?
You can request a quote for O-Methylguanosine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for O-Methylguanosine?
Yes, KEHONG BIO provides custom synthesis services for O-Methylguanosine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.