Quinine, trimethylsilyl ether structure

Quinine, trimethylsilyl ether

TL;DR: Quinine, trimethylsilyl ether (CAS 77981-91-0) is a chemical compound with molecular formula C23H32N2O2Si and molecular weight 396.22 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

[(5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl)-(6-methoxyquinolin-4-yl)methoxy]-trimethylsilane

Also Known As: Quinine, TMS derivative, Quinine, trimethylsilyl ether, 6'-Methoxy-9-[(trimethylsilyl)oxy]cinchonan, J3.295.811G, (9S)-6'-Methoxy-9-[(trimethylsilyl)oxy]cinchonan

CAS: 77981-91-0
Molecular Formula C23H32N2O2Si
Molecular Weight 396.22 g/mol
LogP 5.0324
Topological Polar Surface Area 34.6 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 4
Rotatable Bonds 6
Exact Mass 396.2233
Heavy Atoms 28
Complexity 551.0

Chemical Identifiers

CAS Number 77981-91-0
SMILES COC1=CC2=C(C=CN=C2C=C1)C(C3CC4CCN3CC4C=C)O[Si](C)(C)C
InChIKey UKECXMWGKYEZPW-UHFFFAOYSA-N

Product Overview

Quinine, trimethylsilyl ether (CAS 77981-91-0), with molecular formula C23H32N2O2Si and molecular weight 396.22 g/mol. IUPAC: [(5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl)-(6-methoxyquinolin-4-yl)methoxy]-trimethylsilane.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Quinine, trimethylsilyl ether

XLogP
5.0324
TPSA (Topological Polar Surface Area)
34.6
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
4
Rotatable Bonds
6
Heavy Atoms
28
Complexity
551.0
Exact Mass
396.2233
Monoisotopic Mass
396.2233
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Quinine, trimethylsilyl ether

The XLogP value of 5.0324 indicates that Quinine, trimethylsilyl ether is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 34.6 Ų, Quinine, trimethylsilyl ether exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Quinine, trimethylsilyl ether has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Quinine, trimethylsilyl ether?

The CAS number of Quinine, trimethylsilyl ether is 77981-91-0.

What is the molecular formula of Quinine, trimethylsilyl ether?

The molecular formula of Quinine, trimethylsilyl ether is C23H32N2O2Si.

What is the molecular weight of Quinine, trimethylsilyl ether?

The molecular weight of Quinine, trimethylsilyl ether is 396.22 g/mol.

Where can I buy Quinine, trimethylsilyl ether?

You can request a quote for Quinine, trimethylsilyl ether directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Quinine, trimethylsilyl ether?

Yes, KEHONG BIO provides custom synthesis services for Quinine, trimethylsilyl ether and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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