Pentafluorophenylisothiocyanate structure

Pentafluorophenylisothiocyanate

TL;DR: Pentafluorophenylisothiocyanate (CAS 77977-73-2) is a chemical compound with molecular formula C7F5NS and molecular weight 224.97 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

1,2,3,4,5-pentafluoro-6-isothiocyanatobenzene

Also Known As: Pentafluorophenyl isothiocyanate, Pentafluorophenylisothiocyanate, Perfluorophenyl isothiocyanate, NAPHTHOLAS-BO, Benzene, pentafluoroisothiocyanato-

CAS: 77977-73-2
Molecular Formula C7F5NS
Molecular Weight 224.97 g/mol
LogP 3.8
Topological Polar Surface Area 44.5 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 7
Rotatable Bonds 1
Exact Mass 224.96716
Heavy Atoms 14
Complexity 240.0

Chemical Identifiers

CAS Number 77977-73-2
SMILES C(=NC1=C(C(=C(C(=C1F)F)F)F)F)=S
InChIKey NGNKMRBGZPDABE-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 4 IPC patent classification(s) across the SureChEMBL global patent database.

Analytical Reagents (12 patents) Catalysts (1 patents) Heterocyclic Building Blocks (5 patents) Pharmaceutical Intermediates (4 patents)

Product Overview

Pentafluorophenylisothiocyanate (CAS 77977-73-2), with molecular formula C7F5NS and molecular weight 224.97 g/mol. IUPAC: 1,2,3,4,5-pentafluoro-6-isothiocyanatobenzene.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Pentafluorophenylisothiocyanate

XLogP
3.8
TPSA (Topological Polar Surface Area)
44.5
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
7
Rotatable Bonds
1
Heavy Atoms
14
Complexity
240.0
Exact Mass
224.96716
Monoisotopic Mass
224.96716
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Pentafluorophenylisothiocyanate

The XLogP value of 3.8 indicates that Pentafluorophenylisothiocyanate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 44.5 Ų, Pentafluorophenylisothiocyanate exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Pentafluorophenylisothiocyanate has 0 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Pentafluorophenylisothiocyanate?

The CAS number of Pentafluorophenylisothiocyanate is 77977-73-2.

What is the molecular formula of Pentafluorophenylisothiocyanate?

The molecular formula of Pentafluorophenylisothiocyanate is C7F5NS.

What is the molecular weight of Pentafluorophenylisothiocyanate?

The molecular weight of Pentafluorophenylisothiocyanate is 224.97 g/mol.

Where can I buy Pentafluorophenylisothiocyanate?

You can request a quote for Pentafluorophenylisothiocyanate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Pentafluorophenylisothiocyanate?

Yes, KEHONG BIO provides custom synthesis services for Pentafluorophenylisothiocyanate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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