LH 1
TL;DR: LH 1 (CAS 77862-94-3) is a chemical compound with molecular formula C23H40N2O2 and molecular weight 376.31 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[(3R,5S,8R,9S,10S,13S,14S,17S)-3-[(2-amino-1-hydroxyethyl)amino]-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone
Also Known As: LH 1, 3alpha-N-(2-Aminoethanoyl)amino-5alpha-pregnan-20-one, 1-[(3R,5S,8R,9S,10S,13S,14S,17S)-3-[(2-amino-1-hydroxyethyl)amino]-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone, 3-[(2-Amino-1-hydroxyethyl)amino]pregnan-20-one, 3 alpha-N-(2-aminoethanoyl)amino-5 alpha-pregnan-20-one
| Molecular Formula | C23H40N2O2 |
|---|---|
| Molecular Weight | 376.31 g/mol |
| LogP | 3.7 |
| Topological Polar Surface Area | 75.4 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 376.309 |
| Heavy Atoms | 27 |
| Complexity | 581.0 |
Chemical Identifiers
| CAS Number | 77862-94-3 |
|---|---|
| SMILES | CC(=O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@@H]4[C@@]3(CC[C@H](C4)NC(CN)O)C)C |
| InChIKey | NPLJAFVDHKIFAM-IYCCZKSRSA-N |
Product Overview
LH 1 (CAS 77862-94-3), with molecular formula C23H40N2O2 and molecular weight 376.31 g/mol. IUPAC: 1-[(3R,5S,8R,9S,10S,13S,14S,17S)-3-[(2-amino-1-hydroxyethyl)amino]-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone.
Chemical Property Profile of LH 1
Property Insights of LH 1
The XLogP value of 3.7 indicates that LH 1 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 75.4 Ų falls within the moderate polarity range, balancing permeability and solubility for LH 1. Following Lipinski's Rule of Five, LH 1 has 3 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of LH 1?
The CAS number of LH 1 is 77862-94-3.
What is the molecular formula of LH 1?
The molecular formula of LH 1 is C23H40N2O2.
What is the molecular weight of LH 1?
The molecular weight of LH 1 is 376.31 g/mol.
Where can I buy LH 1?
You can request a quote for LH 1 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for LH 1?
Yes, KEHONG BIO provides custom synthesis services for LH 1 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.