Bcr-abl Inhibitor
TL;DR: Bcr-abl Inhibitor (CAS 778270-11-4) is a chemical compound with molecular formula C18H13F3N4O2 and molecular weight 374.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-[6-[4-(trifluoromethoxy)anilino]pyrimidin-4-yl]benzamide
Also Known As: Bcr-abl Inhibitor, Bcr-abl, 3-(6-((4-(Trifluoromethoxy)phenyl)amino)pyrimidin-4-yl)benzamide, nchembio760-comp2, Bcr-abl inhibitor GNF-2
| Molecular Formula | C18H13F3N4O2 |
|---|---|
| Molecular Weight | 374.10 g/mol |
| LogP | 3.8847 |
| Topological Polar Surface Area | 90.13 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 374.09906 |
| Heavy Atoms | 27 |
| Complexity | 959.3206 |
Chemical Identifiers
| CAS Number | 778270-11-4 |
|---|---|
| SMILES | C1=CC(=CC(=C1)C(=O)N)C2=CC(=NC=N2)NC3=CC=C(C=C3)OC(F)(F)F |
Product Overview
Bcr-abl Inhibitor (CAS 778270-11-4), with molecular formula C18H13F3N4O2 and molecular weight 374.10 g/mol. IUPAC: 3-[6-[4-(trifluoromethoxy)anilino]pyrimidin-4-yl]benzamide.
Chemical Property Profile of Bcr-abl Inhibitor
Property Insights of Bcr-abl Inhibitor
The XLogP value of 3.8847 indicates that Bcr-abl Inhibitor is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 90.13 Ų falls within the moderate polarity range, balancing permeability and solubility for Bcr-abl Inhibitor. Following Lipinski's Rule of Five, Bcr-abl Inhibitor has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Bcr-abl Inhibitor?
The CAS number of Bcr-abl Inhibitor is 778270-11-4.
What is the molecular formula of Bcr-abl Inhibitor?
The molecular formula of Bcr-abl Inhibitor is C18H13F3N4O2.
What is the molecular weight of Bcr-abl Inhibitor?
The molecular weight of Bcr-abl Inhibitor is 374.10 g/mol.
Where can I buy Bcr-abl Inhibitor?
You can request a quote for Bcr-abl Inhibitor directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Bcr-abl Inhibitor?
Yes, KEHONG BIO provides custom synthesis services for Bcr-abl Inhibitor and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.