J384.027A
TL;DR: J384.027A (CAS 77795-95-0) is a chemical compound with molecular formula C22H24F2N2O and molecular weight 370.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[8-fluoro-5-(4-fluorophenyl)-2,3,4,5-tetrahydro-1-benzazepin-1-yl]-2-pyrrolidin-1-ylethanone
Also Known As: AE-641/00192016, 8-fluoro-5-1-2,3,4,5-tetrahydro-1h-1-benzazepine, 8-Fluoro-5-(4-fluorophenyl)-1-(pyrrolizinoacetyl)-2,3,4,5-tetrahydro-1H-1-benzazepine, 1-[8-fluoro-5-(4-fluorophenyl)-2,3,4,5-tetrahydro-1-benzazepin-1-yl]-2-pyrrolidin-1-ylethanone, 8-fluoro-5-(4-fluorophenyl)-1-(1-pyrrolidinylacetyl)-2,3,4,5-tetrahydro-1H-1-benzazepine
| Molecular Formula | C22H24F2N2O |
|---|---|
| Molecular Weight | 370.19 g/mol |
| LogP | 4.2 |
| Topological Polar Surface Area | 23.6 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 370.18567 |
| Heavy Atoms | 27 |
| Complexity | 503.0 |
Chemical Identifiers
| CAS Number | 77795-95-0 |
|---|---|
| SMILES | C1CCN(C1)CC(=O)N2CCCC(C3=C2C=C(C=C3)F)C4=CC=C(C=C4)F |
| InChIKey | GYMSCQAXVNEANR-UHFFFAOYSA-N |
Product Overview
J384.027A (CAS 77795-95-0), with molecular formula C22H24F2N2O and molecular weight 370.19 g/mol. IUPAC: 1-[8-fluoro-5-(4-fluorophenyl)-2,3,4,5-tetrahydro-1-benzazepin-1-yl]-2-pyrrolidin-1-ylethanone.
Chemical Property Profile of J384.027A
Property Insights of J384.027A
The XLogP value of 4.2 indicates that J384.027A is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 23.6 Ų, J384.027A exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, J384.027A has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of J384.027A?
The CAS number of J384.027A is 77795-95-0.
What is the molecular formula of J384.027A?
The molecular formula of J384.027A is C22H24F2N2O.
What is the molecular weight of J384.027A?
The molecular weight of J384.027A is 370.19 g/mol.
Where can I buy J384.027A?
You can request a quote for J384.027A directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for J384.027A?
Yes, KEHONG BIO provides custom synthesis services for J384.027A and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.