![2-[(6-chloro-2-pyridin-3-ylquinoline-4-carbonyl)amino]-N,N,4-trimethyl-1,3-thiazole-5-carboxamide structure](/static/products/7778/777871-50-8.webp)
2-[(6-chloro-2-pyridin-3-ylquinoline-4-carbonyl)amino]-N,N,4-trimethyl-1,3-thiazole-5-carboxamide
TL;DR: 2-[(6-chloro-2-pyridin-3-ylquinoline-4-carbonyl)amino]-N,N,4-trimethyl-1,3-thiazole-5-carboxamide (CAS 777871-50-8) is a chemical compound with molecular formula C22H18ClN5O2S and molecular weight 451.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[(6-chloro-2-pyridin-3-ylquinoline-4-carbonyl)amino]-N,N,4-trimethyl-1,3-thiazole-5-carboxamide
Also Known As: 2-[(6-chloro-2-pyridin-3-ylquinoline-4-carbonyl)amino]-N,N,4-trimethyl-1,3-thiazole-5-carboxamide, {2-[(6-chloro-2-(3-pyridyl)(4-quinolyl))carbonylamino]-4-methyl(1,3-thiazol-5- yl)}-N,N-dimethylcarboxamide, 6-chloro-N-[5-(dimethylcarbamoyl)-4-methyl-1,3-thiazol-2-yl]-2-(pyridin-3-yl)quinoline-4-carboxamide
| Molecular Formula | C22H18ClN5O2S |
|---|---|
| Molecular Weight | 451.09 g/mol |
| LogP | 4.66922 |
| Topological Polar Surface Area | 88.08 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 4 |
| Exact Mass | 451.08698 |
| Heavy Atoms | 31 |
| Complexity | 1304.2577 |
Chemical Identifiers
| CAS Number | 777871-50-8 |
|---|---|
| SMILES | CC1=C(SC(=N1)NC(=O)C2=CC(=NC3=C2C=C(C=C3)Cl)C4=CN=CC=C4)C(=O)N(C)C |
Product Overview
2-[(6-chloro-2-pyridin-3-ylquinoline-4-carbonyl)amino]-N,N,4-trimethyl-1,3-thiazole-5-carboxamide (CAS 777871-50-8), with molecular formula C22H18ClN5O2S and molecular weight 451.09 g/mol. IUPAC: 2-[(6-chloro-2-pyridin-3-ylquinoline-4-carbonyl)amino]-N,N,4-trimethyl-1,3-thiazole-5-carboxamide.
Chemical Property Profile of 2-[(6-chloro-2-pyridin-3-ylquinoline-4-carbonyl)amino]-N,N,4-trimethyl-1,3-thiazole-5-carboxamide
Property Insights of 2-[(6-chloro-2-pyridin-3-ylquinoline-4-carbonyl)amino]-N,N,4-trimethyl-1,3-thiazole-5-carboxamide
The XLogP value of 4.66922 indicates that 2-[(6-chloro-2-pyridin-3-ylquinoline-4-carbonyl)amino]-N,N,4-trimethyl-1,3-thiazole-5-carboxamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 88.08 Ų falls within the moderate polarity range, balancing permeability and solubility for 2-[(6-chloro-2-pyridin-3-ylquinoline-4-carbonyl)amino]-N,N,4-trimethyl-1,3-thiazole-5-carboxamide. Following Lipinski's Rule of Five, 2-[(6-chloro-2-pyridin-3-ylquinoline-4-carbonyl)amino]-N,N,4-trimethyl-1,3-thiazole-5-carboxamide has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-[(6-chloro-2-pyridin-3-ylquinoline-4-carbonyl)amino]-N,N,4-trimethyl-1,3-thiazole-5-carboxamide?
The CAS number of 2-[(6-chloro-2-pyridin-3-ylquinoline-4-carbonyl)amino]-N,N,4-trimethyl-1,3-thiazole-5-carboxamide is 777871-50-8.
What is the molecular formula of 2-[(6-chloro-2-pyridin-3-ylquinoline-4-carbonyl)amino]-N,N,4-trimethyl-1,3-thiazole-5-carboxamide?
The molecular formula of 2-[(6-chloro-2-pyridin-3-ylquinoline-4-carbonyl)amino]-N,N,4-trimethyl-1,3-thiazole-5-carboxamide is C22H18ClN5O2S.
What is the molecular weight of 2-[(6-chloro-2-pyridin-3-ylquinoline-4-carbonyl)amino]-N,N,4-trimethyl-1,3-thiazole-5-carboxamide?
The molecular weight of 2-[(6-chloro-2-pyridin-3-ylquinoline-4-carbonyl)amino]-N,N,4-trimethyl-1,3-thiazole-5-carboxamide is 451.09 g/mol.
Where can I buy 2-[(6-chloro-2-pyridin-3-ylquinoline-4-carbonyl)amino]-N,N,4-trimethyl-1,3-thiazole-5-carboxamide?
You can request a quote for 2-[(6-chloro-2-pyridin-3-ylquinoline-4-carbonyl)amino]-N,N,4-trimethyl-1,3-thiazole-5-carboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-[(6-chloro-2-pyridin-3-ylquinoline-4-carbonyl)amino]-N,N,4-trimethyl-1,3-thiazole-5-carboxamide?
Yes, KEHONG BIO provides custom synthesis services for 2-[(6-chloro-2-pyridin-3-ylquinoline-4-carbonyl)amino]-N,N,4-trimethyl-1,3-thiazole-5-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.