![6-chloro-N-[4-(methylsulfamoyl)phenyl]-2-pyridin-4-ylquinoline-4-carboxamide structure](/static/products/7778/777869-70-2.webp)
6-chloro-N-[4-(methylsulfamoyl)phenyl]-2-pyridin-4-ylquinoline-4-carboxamide
TL;DR: 6-chloro-N-[4-(methylsulfamoyl)phenyl]-2-pyridin-4-ylquinoline-4-carboxamide (CAS 777869-70-2) is a chemical compound with molecular formula C22H17ClN4O3S and molecular weight 452.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-chloro-N-[4-(methylsulfamoyl)phenyl]-2-pyridin-4-ylquinoline-4-carboxamide
Also Known As: 6-chloro-N-[4-(methylsulfamoyl)phenyl]-2-pyridin-4-ylquinoline-4-carboxamide, (6-chloro-2-(4-pyridyl)(4-quinolyl))-N-{4-[(methylamino)sulfonyl]phenyl}carbox amide, 6-chloro-N-[4-(methylsulfamoyl)phenyl]-2-(pyridin-4-yl)quinoline-4-carboxamide, 6-chloro-N-[4-(methylsulfamoyl)phenyl]-2-pyridin-4-yl-quinoline-4-carboxamide
| Molecular Formula | C22H17ClN4O3S |
|---|---|
| Molecular Weight | 452.07 g/mol |
| LogP | 4.1106 |
| Topological Polar Surface Area | 101.05 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 452.07098 |
| Heavy Atoms | 31 |
| Complexity | 1375.5577 |
Chemical Identifiers
| CAS Number | 777869-70-2 |
|---|---|
| SMILES | CNS(=O)(=O)C1=CC=C(C=C1)NC(=O)C2=CC(=NC3=C2C=C(C=C3)Cl)C4=CC=NC=C4 |
Product Overview
6-chloro-N-[4-(methylsulfamoyl)phenyl]-2-pyridin-4-ylquinoline-4-carboxamide (CAS 777869-70-2), with molecular formula C22H17ClN4O3S and molecular weight 452.07 g/mol. IUPAC: 6-chloro-N-[4-(methylsulfamoyl)phenyl]-2-pyridin-4-ylquinoline-4-carboxamide.
Chemical Property Profile of 6-chloro-N-[4-(methylsulfamoyl)phenyl]-2-pyridin-4-ylquinoline-4-carboxamide
Property Insights of 6-chloro-N-[4-(methylsulfamoyl)phenyl]-2-pyridin-4-ylquinoline-4-carboxamide
The XLogP value of 4.1106 indicates that 6-chloro-N-[4-(methylsulfamoyl)phenyl]-2-pyridin-4-ylquinoline-4-carboxamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 101.05 Ų falls within the moderate polarity range, balancing permeability and solubility for 6-chloro-N-[4-(methylsulfamoyl)phenyl]-2-pyridin-4-ylquinoline-4-carboxamide. Following Lipinski's Rule of Five, 6-chloro-N-[4-(methylsulfamoyl)phenyl]-2-pyridin-4-ylquinoline-4-carboxamide has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 6-chloro-N-[4-(methylsulfamoyl)phenyl]-2-pyridin-4-ylquinoline-4-carboxamide?
The CAS number of 6-chloro-N-[4-(methylsulfamoyl)phenyl]-2-pyridin-4-ylquinoline-4-carboxamide is 777869-70-2.
What is the molecular formula of 6-chloro-N-[4-(methylsulfamoyl)phenyl]-2-pyridin-4-ylquinoline-4-carboxamide?
The molecular formula of 6-chloro-N-[4-(methylsulfamoyl)phenyl]-2-pyridin-4-ylquinoline-4-carboxamide is C22H17ClN4O3S.
What is the molecular weight of 6-chloro-N-[4-(methylsulfamoyl)phenyl]-2-pyridin-4-ylquinoline-4-carboxamide?
The molecular weight of 6-chloro-N-[4-(methylsulfamoyl)phenyl]-2-pyridin-4-ylquinoline-4-carboxamide is 452.07 g/mol.
Where can I buy 6-chloro-N-[4-(methylsulfamoyl)phenyl]-2-pyridin-4-ylquinoline-4-carboxamide?
You can request a quote for 6-chloro-N-[4-(methylsulfamoyl)phenyl]-2-pyridin-4-ylquinoline-4-carboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 6-chloro-N-[4-(methylsulfamoyl)phenyl]-2-pyridin-4-ylquinoline-4-carboxamide?
Yes, KEHONG BIO provides custom synthesis services for 6-chloro-N-[4-(methylsulfamoyl)phenyl]-2-pyridin-4-ylquinoline-4-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.