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3-(thiophen-2-yl)-3,4-dihydrobenzimidazo[2,1-b]quinazolin-1(2H)-one
TL;DR: 3-(thiophen-2-yl)-3,4-dihydrobenzimidazo[2,1-b]quinazolin-1(2H)-one (CAS 777867-50-2) is a chemical compound with molecular formula C18H13N3OS and molecular weight 319.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-thiophen-2-yl-3,4-dihydro-2H-benzimidazolo[2,1-b]quinazolin-1-one
Also Known As: BAS 12290604, 3-(thiophen-2-yl)-3,4-dihydrobenzimidazo[2,1-b]quinazolin-1(2H)-one, 3-(2-thienyl)-2,3,4,11-tetrahydrobenzimidazolo[2,1-b]quinazolin-1-one, 3-thiophen-2-yl-3,4-dihydro-2H-benzimidazolo[2,1-b]quinazolin-1-one, 8-Thiophen-2-yl-8,9-dihydro-7H-4b,10,11-triaza-benzo[b]fluoren-6-one
| Molecular Formula | C18H13N3OS |
|---|---|
| Molecular Weight | 319.08 g/mol |
| LogP | 3.8567 |
| Topological Polar Surface Area | 47.26 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 319.07794 |
| Heavy Atoms | 23 |
| Complexity | 1048.9535 |
Chemical Identifiers
| CAS Number | 777867-50-2 |
|---|---|
| SMILES | C1C(CC(=O)C2=CN3C4=CC=CC=C4N=C3N=C21)C5=CC=CS5 |
Product Overview
3-(thiophen-2-yl)-3,4-dihydrobenzimidazo[2,1-b]quinazolin-1(2H)-one (CAS 777867-50-2), with molecular formula C18H13N3OS and molecular weight 319.08 g/mol. IUPAC: 3-thiophen-2-yl-3,4-dihydro-2H-benzimidazolo[2,1-b]quinazolin-1-one.
Chemical Property Profile of 3-(thiophen-2-yl)-3,4-dihydrobenzimidazo[2,1-b]quinazolin-1(2H)-one
Property Insights of 3-(thiophen-2-yl)-3,4-dihydrobenzimidazo[2,1-b]quinazolin-1(2H)-one
The XLogP value of 3.8567 indicates that 3-(thiophen-2-yl)-3,4-dihydrobenzimidazo[2,1-b]quinazolin-1(2H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 47.26 Ų, 3-(thiophen-2-yl)-3,4-dihydrobenzimidazo[2,1-b]quinazolin-1(2H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 3-(thiophen-2-yl)-3,4-dihydrobenzimidazo[2,1-b]quinazolin-1(2H)-one has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3-(thiophen-2-yl)-3,4-dihydrobenzimidazo[2,1-b]quinazolin-1(2H)-one?
The CAS number of 3-(thiophen-2-yl)-3,4-dihydrobenzimidazo[2,1-b]quinazolin-1(2H)-one is 777867-50-2.
What is the molecular formula of 3-(thiophen-2-yl)-3,4-dihydrobenzimidazo[2,1-b]quinazolin-1(2H)-one?
The molecular formula of 3-(thiophen-2-yl)-3,4-dihydrobenzimidazo[2,1-b]quinazolin-1(2H)-one is C18H13N3OS.
What is the molecular weight of 3-(thiophen-2-yl)-3,4-dihydrobenzimidazo[2,1-b]quinazolin-1(2H)-one?
The molecular weight of 3-(thiophen-2-yl)-3,4-dihydrobenzimidazo[2,1-b]quinazolin-1(2H)-one is 319.08 g/mol.
Where can I buy 3-(thiophen-2-yl)-3,4-dihydrobenzimidazo[2,1-b]quinazolin-1(2H)-one?
You can request a quote for 3-(thiophen-2-yl)-3,4-dihydrobenzimidazo[2,1-b]quinazolin-1(2H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3-(thiophen-2-yl)-3,4-dihydrobenzimidazo[2,1-b]quinazolin-1(2H)-one?
Yes, KEHONG BIO provides custom synthesis services for 3-(thiophen-2-yl)-3,4-dihydrobenzimidazo[2,1-b]quinazolin-1(2H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.