2-(4-benzylpiperazin-1-yl)-7-(2-fluorophenyl)-4-methyl-7,8-dihydroquinazolin-5(6H)-one
TL;DR: 2-(4-benzylpiperazin-1-yl)-7-(2-fluorophenyl)-4-methyl-7,8-dihydroquinazolin-5(6H)-one (CAS 777866-72-5) is a chemical compound with molecular formula C26H27FN4O and molecular weight 430.22 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-(4-benzylpiperazin-1-yl)-7-(2-fluorophenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one
Also Known As: 2-(4-benzylpiperazin-1-yl)-7-(2-fluorophenyl)-4-methyl-7,8-dihydroquinazolin-5(6H)-one, 2-(4-benzylpiperazin-1-yl)-7-(2-fluorophenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one, 7-(2-fluorophenyl)-4-methyl-2-[4-benzylpiperazinyl]-6,7,8-trihydroquinazolin-5 -one, 2-(4-BENZYLPIPERAZINO)-7-(2-FLUOROPHENYL)-4-METHYL-7,8-DIHYDRO-5(6H)-QUINAZOLINONE
| Molecular Formula | C26H27FN4O |
|---|---|
| Molecular Weight | 430.22 g/mol |
| LogP | 4.15902 |
| Topological Polar Surface Area | 49.33 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 430.2169 |
| Heavy Atoms | 32 |
| Complexity | 1125.9258 |
Chemical Identifiers
| CAS Number | 777866-72-5 |
|---|---|
| SMILES | CC1=C2C(=NC(=N1)N3CCN(CC3)CC4=CC=CC=C4)CC(CC2=O)C5=CC=CC=C5F |
Product Overview
2-(4-benzylpiperazin-1-yl)-7-(2-fluorophenyl)-4-methyl-7,8-dihydroquinazolin-5(6H)-one (CAS 777866-72-5), with molecular formula C26H27FN4O and molecular weight 430.22 g/mol. IUPAC: 2-(4-benzylpiperazin-1-yl)-7-(2-fluorophenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one.
Chemical Property Profile of 2-(4-benzylpiperazin-1-yl)-7-(2-fluorophenyl)-4-methyl-7,8-dihydroquinazolin-5(6H)-one
Property Insights of 2-(4-benzylpiperazin-1-yl)-7-(2-fluorophenyl)-4-methyl-7,8-dihydroquinazolin-5(6H)-one
The XLogP value of 4.15902 indicates that 2-(4-benzylpiperazin-1-yl)-7-(2-fluorophenyl)-4-methyl-7,8-dihydroquinazolin-5(6H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 49.33 Ų, 2-(4-benzylpiperazin-1-yl)-7-(2-fluorophenyl)-4-methyl-7,8-dihydroquinazolin-5(6H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-(4-benzylpiperazin-1-yl)-7-(2-fluorophenyl)-4-methyl-7,8-dihydroquinazolin-5(6H)-one has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-(4-benzylpiperazin-1-yl)-7-(2-fluorophenyl)-4-methyl-7,8-dihydroquinazolin-5(6H)-one?
The CAS number of 2-(4-benzylpiperazin-1-yl)-7-(2-fluorophenyl)-4-methyl-7,8-dihydroquinazolin-5(6H)-one is 777866-72-5.
What is the molecular formula of 2-(4-benzylpiperazin-1-yl)-7-(2-fluorophenyl)-4-methyl-7,8-dihydroquinazolin-5(6H)-one?
The molecular formula of 2-(4-benzylpiperazin-1-yl)-7-(2-fluorophenyl)-4-methyl-7,8-dihydroquinazolin-5(6H)-one is C26H27FN4O.
What is the molecular weight of 2-(4-benzylpiperazin-1-yl)-7-(2-fluorophenyl)-4-methyl-7,8-dihydroquinazolin-5(6H)-one?
The molecular weight of 2-(4-benzylpiperazin-1-yl)-7-(2-fluorophenyl)-4-methyl-7,8-dihydroquinazolin-5(6H)-one is 430.22 g/mol.
Where can I buy 2-(4-benzylpiperazin-1-yl)-7-(2-fluorophenyl)-4-methyl-7,8-dihydroquinazolin-5(6H)-one?
You can request a quote for 2-(4-benzylpiperazin-1-yl)-7-(2-fluorophenyl)-4-methyl-7,8-dihydroquinazolin-5(6H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-(4-benzylpiperazin-1-yl)-7-(2-fluorophenyl)-4-methyl-7,8-dihydroquinazolin-5(6H)-one?
Yes, KEHONG BIO provides custom synthesis services for 2-(4-benzylpiperazin-1-yl)-7-(2-fluorophenyl)-4-methyl-7,8-dihydroquinazolin-5(6H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.