8-(2-Diethylaminoethyl-thio)-4-(1-oxidothiomorpholino)-2-piperazino-pyrimido(5,4-d)pyrimidine structure

8-(2-Diethylaminoethyl-thio)-4-(1-oxidothiomorpholino)-2-piperazino-pyrimido(5,4-d)pyrimidine

TL;DR: 8-(2-Diethylaminoethyl-thio)-4-(1-oxidothiomorpholino)-2-piperazino-pyrimido(5,4-d)pyrimidine (CAS 77776-86-4) is a chemical compound with molecular formula C20H32N8OS2 and molecular weight 464.21 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

N,N-diethyl-2-[4-(1-oxo-1,4-thiazinan-4-yl)-2-piperazin-1-ylpyrimido[5,4-d]pyrimidin-8-yl]sulfanylethanamine

Also Known As: 8-(2-Diethylaminoethyl-thio)-4-(1-oxidothiomorpholino)-2-piperazino-pyrimido(5,4-d)pyrimidine, Ethanamine, N,N-diethyl-2-((6-(1-piperazinyl)-8-(4-thiomorpholinyl)pyrimido(5,4-d)pyrimidin-4-yl)thio)-, S-oxide, 4-[8-{[2-(Diethylamino)ethyl]sulfanyl}-2-(piperazin-1-yl)pyrimido[5,4-d]pyrimidin-4-yl]-1lambda~4~-thiomorpholin-1-one, N,N-diethyl-2-[4-(1-oxo-1,4-thiazinan-4-yl)-2-piperazin-1-ylpyrimido[5,4-d]pyrimidin-8-yl]sulfanylethanamine, RefChem:339862

CAS: 77776-86-4
Molecular Formula C20H32N8OS2
Molecular Weight 464.21 g/mol
LogP 0.832
Topological Polar Surface Area 90.38 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 10
Rotatable Bonds 8
Exact Mass 464.21405
Heavy Atoms 31
Complexity 894.12396

Chemical Identifiers

CAS Number 77776-86-4
SMILES CCN(CC)CCSC1=NC=NC2=C1N=C(N=C2N3CCS(=O)CC3)N4CCNCC4

Product Overview

8-(2-Diethylaminoethyl-thio)-4-(1-oxidothiomorpholino)-2-piperazino-pyrimido(5,4-d)pyrimidine (CAS 77776-86-4), with molecular formula C20H32N8OS2 and molecular weight 464.21 g/mol. IUPAC: N,N-diethyl-2-[4-(1-oxo-1,4-thiazinan-4-yl)-2-piperazin-1-ylpyrimido[5,4-d]pyrimidin-8-yl]sulfanylethanamine.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 8-(2-Diethylaminoethyl-thio)-4-(1-oxidothiomorpholino)-2-piperazino-pyrimido(5,4-d)pyrimidine

XLogP
0.832
TPSA (Topological Polar Surface Area)
90.38
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
10
Rotatable Bonds
8
Heavy Atoms
31
Complexity
894.12396
Exact Mass
464.21405
Monoisotopic Mass
464.21405
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 8-(2-Diethylaminoethyl-thio)-4-(1-oxidothiomorpholino)-2-piperazino-pyrimido(5,4-d)pyrimidine

The XLogP value of 0.832 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 8-(2-Diethylaminoethyl-thio)-4-(1-oxidothiomorpholino)-2-piperazino-pyrimido(5,4-d)pyrimidine. The TPSA of 90.38 Ų falls within the moderate polarity range, balancing permeability and solubility for 8-(2-Diethylaminoethyl-thio)-4-(1-oxidothiomorpholino)-2-piperazino-pyrimido(5,4-d)pyrimidine. Following Lipinski's Rule of Five, 8-(2-Diethylaminoethyl-thio)-4-(1-oxidothiomorpholino)-2-piperazino-pyrimido(5,4-d)pyrimidine has 1 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 8-(2-Diethylaminoethyl-thio)-4-(1-oxidothiomorpholino)-2-piperazino-pyrimido(5,4-d)pyrimidine?

The CAS number of 8-(2-Diethylaminoethyl-thio)-4-(1-oxidothiomorpholino)-2-piperazino-pyrimido(5,4-d)pyrimidine is 77776-86-4.

What is the molecular formula of 8-(2-Diethylaminoethyl-thio)-4-(1-oxidothiomorpholino)-2-piperazino-pyrimido(5,4-d)pyrimidine?

The molecular formula of 8-(2-Diethylaminoethyl-thio)-4-(1-oxidothiomorpholino)-2-piperazino-pyrimido(5,4-d)pyrimidine is C20H32N8OS2.

What is the molecular weight of 8-(2-Diethylaminoethyl-thio)-4-(1-oxidothiomorpholino)-2-piperazino-pyrimido(5,4-d)pyrimidine?

The molecular weight of 8-(2-Diethylaminoethyl-thio)-4-(1-oxidothiomorpholino)-2-piperazino-pyrimido(5,4-d)pyrimidine is 464.21 g/mol.

Where can I buy 8-(2-Diethylaminoethyl-thio)-4-(1-oxidothiomorpholino)-2-piperazino-pyrimido(5,4-d)pyrimidine?

You can request a quote for 8-(2-Diethylaminoethyl-thio)-4-(1-oxidothiomorpholino)-2-piperazino-pyrimido(5,4-d)pyrimidine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 8-(2-Diethylaminoethyl-thio)-4-(1-oxidothiomorpholino)-2-piperazino-pyrimido(5,4-d)pyrimidine?

Yes, KEHONG BIO provides custom synthesis services for 8-(2-Diethylaminoethyl-thio)-4-(1-oxidothiomorpholino)-2-piperazino-pyrimido(5,4-d)pyrimidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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