Amicoumacin B structure

Amicoumacin B

TL;DR: Amicoumacin B (CAS 77674-99-8) is a chemical compound with molecular formula C20H28N2O8 and molecular weight 424.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

3-amino-4,5-dihydroxy-6-[[1-(8-hydroxy-1-oxo-3,4-dihydroisochromen-3-yl)-3-methylbutyl]amino]-6-oxohexanoic acid

Also Known As: Amicoumacin B, AI 77B, 3-amino-4,5-dihydroxy-6-[[1-(8-hydroxy-1-oxo-3,4-dihydroisochromen-3-yl)-3-methylbutyl]amino]-6-oxohexanoic acid, 3-amino-4,5-dihydroxy-5-[[1-(8-hydroxy-1-oxo-isochroman-3-yl)-3-methyl -butyl]carbamoyl]pentanoic acid, 3-amino-4,5-dihydroxy-5-[[1- -3-methyl-butyl]carbamoyl]pentanoicacid

CAS: 77674-99-8
Molecular Formula C20H28N2O8
Molecular Weight 424.18 g/mol
LogP -1.8
Topological Polar Surface Area 179.0 Ų
Hydrogen Bond Donors 6
Hydrogen Bond Acceptors 9
Rotatable Bonds 9
Exact Mass 424.18457
Heavy Atoms 30
Complexity 628.0

Chemical Identifiers

CAS Number 77674-99-8
SMILES CC(C)CC(C1CC2=C(C(=CC=C2)O)C(=O)O1)NC(=O)C(C(C(CC(=O)O)N)O)O
InChIKey LOXFXXGTOVWWQV-UHFFFAOYSA-N

Product Overview

Amicoumacin B (CAS 77674-99-8), with molecular formula C20H28N2O8 and molecular weight 424.18 g/mol. IUPAC: 3-amino-4,5-dihydroxy-6-[[1-(8-hydroxy-1-oxo-3,4-dihydroisochromen-3-yl)-3-methylbutyl]amino]-6-oxohexanoic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Amicoumacin B

XLogP
-1.8
TPSA (Topological Polar Surface Area)
179.0
Hydrogen Bond Donors
6
Hydrogen Bond Acceptors
9
Rotatable Bonds
9
Heavy Atoms
30
Complexity
628.0
Exact Mass
424.18457
Monoisotopic Mass
424.18457
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Amicoumacin B

The XLogP value of -1.8 indicates that Amicoumacin B is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 179.0 Ų indicates high polarity, suggesting Amicoumacin B may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Amicoumacin B has 6 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Amicoumacin B?

The CAS number of Amicoumacin B is 77674-99-8.

What is the molecular formula of Amicoumacin B?

The molecular formula of Amicoumacin B is C20H28N2O8.

What is the molecular weight of Amicoumacin B?

The molecular weight of Amicoumacin B is 424.18 g/mol.

Where can I buy Amicoumacin B?

You can request a quote for Amicoumacin B directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Amicoumacin B?

Yes, KEHONG BIO provides custom synthesis services for Amicoumacin B and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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