Proterguride
TL;DR: Proterguride (CAS 77650-95-4) is a chemical compound with molecular formula C22H32N4O and molecular weight 368.26 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-[(6aR,9S,10aR)-7-propyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinolin-9-yl]-1,1-diethylurea
Also Known As: Proterguride, Protergurida, Proterguridum, Proterguride [INN], Proterguridum [Latin]
| Molecular Formula | C22H32N4O |
|---|---|
| Molecular Weight | 368.26 g/mol |
| LogP | 3.4 |
| Topological Polar Surface Area | 51.4 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 5 |
| Exact Mass | 368.2576 |
| Heavy Atoms | 27 |
| Complexity | 522.0 |
Chemical Identifiers
| CAS Number | 77650-95-4 |
|---|---|
| SMILES | CCCN1C[C@H](C[C@H]2[C@H]1CC3=CNC4=CC=CC2=C34)NC(=O)N(CC)CC |
| InChIKey | FCRJELOYDVBTGW-ILZDJORESA-N |
Patent-Derived Application Labels
Derived from 5 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Proterguride (CAS 77650-95-4), with molecular formula C22H32N4O and molecular weight 368.26 g/mol. IUPAC: 3-[(6aR,9S,10aR)-7-propyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinolin-9-yl]-1,1-diethylurea.
Chemical Property Profile of Proterguride
Property Insights of Proterguride
The XLogP value of 3.4 indicates that Proterguride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 51.4 Ų, Proterguride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Proterguride has 2 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Proterguride?
The CAS number of Proterguride is 77650-95-4.
What is the molecular formula of Proterguride?
The molecular formula of Proterguride is C22H32N4O.
What is the molecular weight of Proterguride?
The molecular weight of Proterguride is 368.26 g/mol.
Where can I buy Proterguride?
You can request a quote for Proterguride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Proterguride?
Yes, KEHONG BIO provides custom synthesis services for Proterguride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.