6 Alpha-hydroxy(allo)tetrahydrocortisone
TL;DR: 6 Alpha-hydroxy(allo)tetrahydrocortisone (CAS 7756-78-7) is a chemical compound with molecular formula C21H32O6 and molecular weight 380.22 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(3R,5S,6S,8S,9S,10S,13S,14S,17R)-3,6,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,3,4,5,6,7,8,9,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-11-one
Also Known As: 3,6,17,21-Tetrahydroxypregnane-11,20-dione, 6alpha-Hydroxy(allo)tetrahydrocortisone, 6 Alpha-hydroxy(allo)tetrahydrocortisone, Pregnane-11,20-dione, 3,6,17,21-tetrahydroxy-, (3alpha,5alpha,6alpha)-, (3R,5S,6S,8S,9S,10S,13S,14S,17R)-3,6,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,3,4,5,6,7,8,9,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-11-one
| Molecular Formula | C21H32O6 |
|---|---|
| Molecular Weight | 380.22 g/mol |
| LogP | 0.8 |
| Topological Polar Surface Area | 115.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 2 |
| Exact Mass | 380.21988 |
| Heavy Atoms | 27 |
| Complexity | 663.0 |
Chemical Identifiers
| CAS Number | 7756-78-7 |
|---|---|
| SMILES | C[C@]12CC[C@H](C[C@@H]1[C@H](C[C@@H]3[C@@H]2C(=O)C[C@]4([C@H]3CC[C@@]4(C(=O)CO)O)C)O)O |
| InChIKey | BABPAGUDXMPHFU-YEMCHMRASA-N |
Product Overview
6 Alpha-hydroxy(allo)tetrahydrocortisone (CAS 7756-78-7), with molecular formula C21H32O6 and molecular weight 380.22 g/mol. IUPAC: (3R,5S,6S,8S,9S,10S,13S,14S,17R)-3,6,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,3,4,5,6,7,8,9,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-11-one.
Chemical Property Profile of 6 Alpha-hydroxy(allo)tetrahydrocortisone
Property Insights of 6 Alpha-hydroxy(allo)tetrahydrocortisone
The XLogP value of 0.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 6 Alpha-hydroxy(allo)tetrahydrocortisone. The TPSA of 115.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 6 Alpha-hydroxy(allo)tetrahydrocortisone. Following Lipinski's Rule of Five, 6 Alpha-hydroxy(allo)tetrahydrocortisone has 4 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 6 Alpha-hydroxy(allo)tetrahydrocortisone?
The CAS number of 6 Alpha-hydroxy(allo)tetrahydrocortisone is 7756-78-7.
What is the molecular formula of 6 Alpha-hydroxy(allo)tetrahydrocortisone?
The molecular formula of 6 Alpha-hydroxy(allo)tetrahydrocortisone is C21H32O6.
What is the molecular weight of 6 Alpha-hydroxy(allo)tetrahydrocortisone?
The molecular weight of 6 Alpha-hydroxy(allo)tetrahydrocortisone is 380.22 g/mol.
Where can I buy 6 Alpha-hydroxy(allo)tetrahydrocortisone?
You can request a quote for 6 Alpha-hydroxy(allo)tetrahydrocortisone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 6 Alpha-hydroxy(allo)tetrahydrocortisone?
Yes, KEHONG BIO provides custom synthesis services for 6 Alpha-hydroxy(allo)tetrahydrocortisone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.