6-Chloro-3-(4-chlorophenyl)-2,4-bis(2-fluorophenyl)-3,4-dihydroquinazolin-4-ol
TL;DR: 6-Chloro-3-(4-chlorophenyl)-2,4-bis(2-fluorophenyl)-3,4-dihydroquinazolin-4-ol (CAS 77549-03-2) is a chemical compound with molecular formula C26H16Cl2F2N2O and molecular weight 480.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-chloro-3-(4-chlorophenyl)-2,4-bis(2-fluorophenyl)quinazolin-4-ol
Also Known As: EINECS 278-721-7, 6-Chloro-3-(4-chlorophenyl)-2,4-bis(2-fluorophenyl)-3,4-dihydroquinazolin-4-ol, 6-chloro-3-(4-chlorophenyl)-2,4-bis(2-fluorophenyl)quinazolin-4-ol, 4-Quinazolinol,6-chloro-3-(4-chlorophenyl)-2,4-bis(2-fluorophenyl)-3,4-dihydro-
| Molecular Formula | C26H16Cl2F2N2O |
|---|---|
| Molecular Weight | 480.06 g/mol |
| LogP | 7.0635 |
| Topological Polar Surface Area | 35.83 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 480.06076 |
| Heavy Atoms | 33 |
| Complexity | 1391.4429 |
Chemical Identifiers
| CAS Number | 77549-03-2 |
|---|---|
| SMILES | C1=CC=C(C(=C1)C2=NC3=C(C=C(C=C3)Cl)C(N2C4=CC=C(C=C4)Cl)(C5=CC=CC=C5F)O)F |
Product Overview
6-Chloro-3-(4-chlorophenyl)-2,4-bis(2-fluorophenyl)-3,4-dihydroquinazolin-4-ol (CAS 77549-03-2), with molecular formula C26H16Cl2F2N2O and molecular weight 480.06 g/mol. IUPAC: 6-chloro-3-(4-chlorophenyl)-2,4-bis(2-fluorophenyl)quinazolin-4-ol.
Chemical Property Profile of 6-Chloro-3-(4-chlorophenyl)-2,4-bis(2-fluorophenyl)-3,4-dihydroquinazolin-4-ol
Property Insights of 6-Chloro-3-(4-chlorophenyl)-2,4-bis(2-fluorophenyl)-3,4-dihydroquinazolin-4-ol
The XLogP value of 7.0635 indicates that 6-Chloro-3-(4-chlorophenyl)-2,4-bis(2-fluorophenyl)-3,4-dihydroquinazolin-4-ol is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 35.83 Ų, 6-Chloro-3-(4-chlorophenyl)-2,4-bis(2-fluorophenyl)-3,4-dihydroquinazolin-4-ol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 6-Chloro-3-(4-chlorophenyl)-2,4-bis(2-fluorophenyl)-3,4-dihydroquinazolin-4-ol has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 6-Chloro-3-(4-chlorophenyl)-2,4-bis(2-fluorophenyl)-3,4-dihydroquinazolin-4-ol?
The CAS number of 6-Chloro-3-(4-chlorophenyl)-2,4-bis(2-fluorophenyl)-3,4-dihydroquinazolin-4-ol is 77549-03-2.
What is the molecular formula of 6-Chloro-3-(4-chlorophenyl)-2,4-bis(2-fluorophenyl)-3,4-dihydroquinazolin-4-ol?
The molecular formula of 6-Chloro-3-(4-chlorophenyl)-2,4-bis(2-fluorophenyl)-3,4-dihydroquinazolin-4-ol is C26H16Cl2F2N2O.
What is the molecular weight of 6-Chloro-3-(4-chlorophenyl)-2,4-bis(2-fluorophenyl)-3,4-dihydroquinazolin-4-ol?
The molecular weight of 6-Chloro-3-(4-chlorophenyl)-2,4-bis(2-fluorophenyl)-3,4-dihydroquinazolin-4-ol is 480.06 g/mol.
Where can I buy 6-Chloro-3-(4-chlorophenyl)-2,4-bis(2-fluorophenyl)-3,4-dihydroquinazolin-4-ol?
You can request a quote for 6-Chloro-3-(4-chlorophenyl)-2,4-bis(2-fluorophenyl)-3,4-dihydroquinazolin-4-ol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 6-Chloro-3-(4-chlorophenyl)-2,4-bis(2-fluorophenyl)-3,4-dihydroquinazolin-4-ol?
Yes, KEHONG BIO provides custom synthesis services for 6-Chloro-3-(4-chlorophenyl)-2,4-bis(2-fluorophenyl)-3,4-dihydroquinazolin-4-ol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.