L-8-Oxotetrahydropalmatine
TL;DR: L-8-Oxotetrahydropalmatine (CAS 77519-57-4) is a chemical compound with molecular formula C21H23NO5 and molecular weight 369.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(13aS)-2,3,9,10-tetramethoxy-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinolin-8-one
Also Known As: L-8-Oxotetrahydropalmatine, LHRH, Cleu(7)-, 8H-Dibenzo(a,g)quinolizin-8-one, 5,6,13,13a-tetrahydro-2,3,9,10-tetramethoxy-, (S)-, (13aS)-2,3,9,10-tetramethoxy-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinolin-8-one, (13aS)-2,3,9,10-Tetramethoxy-5,6,13,13a-tetrahydro-8H-isoquinolino[3,2-a]isoquinolin-8-one
| Molecular Formula | C21H23NO5 |
|---|---|
| Molecular Weight | 369.16 g/mol |
| LogP | 2.9 |
| Topological Polar Surface Area | 57.2 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 369.15762 |
| Heavy Atoms | 27 |
| Complexity | 543.0 |
Chemical Identifiers
| CAS Number | 77519-57-4 |
|---|---|
| SMILES | COC1=C(C2=C(C[C@H]3C4=CC(=C(C=C4CCN3C2=O)OC)OC)C=C1)OC |
| InChIKey | DMFHLLHXYQJPJS-HNNXBMFYSA-N |
Product Overview
L-8-Oxotetrahydropalmatine (CAS 77519-57-4), with molecular formula C21H23NO5 and molecular weight 369.16 g/mol. IUPAC: (13aS)-2,3,9,10-tetramethoxy-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinolin-8-one.
Chemical Property Profile of L-8-Oxotetrahydropalmatine
Property Insights of L-8-Oxotetrahydropalmatine
The XLogP value of 2.9 suggests moderate lipophilicity, balancing water solubility and membrane permeability for L-8-Oxotetrahydropalmatine. With a topological polar surface area (TPSA) of 57.2 Ų, L-8-Oxotetrahydropalmatine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, L-8-Oxotetrahydropalmatine has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of L-8-Oxotetrahydropalmatine?
The CAS number of L-8-Oxotetrahydropalmatine is 77519-57-4.
What is the molecular formula of L-8-Oxotetrahydropalmatine?
The molecular formula of L-8-Oxotetrahydropalmatine is C21H23NO5.
What is the molecular weight of L-8-Oxotetrahydropalmatine?
The molecular weight of L-8-Oxotetrahydropalmatine is 369.16 g/mol.
Where can I buy L-8-Oxotetrahydropalmatine?
You can request a quote for L-8-Oxotetrahydropalmatine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for L-8-Oxotetrahydropalmatine?
Yes, KEHONG BIO provides custom synthesis services for L-8-Oxotetrahydropalmatine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.