Tolpadol
TL;DR: Tolpadol (CAS 77502-27-3) is a chemical compound with molecular formula C28H26N4O2 and molecular weight 450.21 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-methyl-N-[2-[(2-methylbenzoyl)amino]-1,2-dipyridin-4-ylethyl]benzamide
Also Known As: Tolpadol, Tolpadolum, Tolpadol [INN], Tolpadolum [Latin], Tolpadolum (Latin)
| Molecular Formula | C28H26N4O2 |
|---|---|
| Molecular Weight | 450.21 g/mol |
| LogP | 3.8 |
| Topological Polar Surface Area | 84.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 7 |
| Exact Mass | 450.20557 |
| Heavy Atoms | 34 |
| Complexity | 603.0 |
Chemical Identifiers
| CAS Number | 77502-27-3 |
|---|---|
| SMILES | CC1=CC=CC=C1C(=O)NC(C2=CC=NC=C2)C(C3=CC=NC=C3)NC(=O)C4=CC=CC=C4C |
| InChIKey | XOCZGIFMFBFPGQ-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 8 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Tolpadol (CAS 77502-27-3), with molecular formula C28H26N4O2 and molecular weight 450.21 g/mol. IUPAC: 2-methyl-N-[2-[(2-methylbenzoyl)amino]-1,2-dipyridin-4-ylethyl]benzamide.
Chemical Property Profile of Tolpadol
Property Insights of Tolpadol
The XLogP value of 3.8 indicates that Tolpadol is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 84.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Tolpadol. Following Lipinski's Rule of Five, Tolpadol has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Tolpadol?
The CAS number of Tolpadol is 77502-27-3.
What is the molecular formula of Tolpadol?
The molecular formula of Tolpadol is C28H26N4O2.
What is the molecular weight of Tolpadol?
The molecular weight of Tolpadol is 450.21 g/mol.
Where can I buy Tolpadol?
You can request a quote for Tolpadol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Tolpadol?
Yes, KEHONG BIO provides custom synthesis services for Tolpadol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.