![4-{[4-(Phenylsulfonyl)-1-piperazinyl]carbonyl}-2-(2-thienyl)quinoline structure](/static/products/7745/774575-05-2.webp)
4-{[4-(Phenylsulfonyl)-1-piperazinyl]carbonyl}-2-(2-thienyl)quinoline
TL;DR: 4-{[4-(Phenylsulfonyl)-1-piperazinyl]carbonyl}-2-(2-thienyl)quinoline (CAS 774575-05-2) is a chemical compound with molecular formula C24H21N3O3S2 and molecular weight 463.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[4-(benzenesulfonyl)piperazin-1-yl]-(2-thiophen-2-ylquinolin-4-yl)methanone
Also Known As: [4-(benzenesulfonyl)piperazin-1-yl]-(2-thiophen-2-ylquinolin-4-yl)methanone|4-(phenylsulfonyl)piperazinyl 2-(2-thienyl)(4-quinolyl) ketone|4-{[4-(phenylsulfonyl)-1-piperazinyl]carbonyl}-2-(2-thienyl)quinoline|[4-(phenylsulfonyl)piperazin-1-yl][2-(thiophen-2-yl)quinolin-4-yl]methanone|SMR000136173|MLS000531195|MLS002547462
| Molecular Formula | C24H21N3O3S2 |
|---|---|
| Molecular Weight | 463.10 g/mol |
| LogP | 4.11 |
| Topological Polar Surface Area | 70.58 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 463.10245 |
| Heavy Atoms | 32 |
| Complexity | 1362.4088 |
Chemical Identifiers
| CAS Number | 774575-05-2 |
|---|---|
| SMILES | C1CN(CCN1C(=O)C2=CC(=NC3=CC=CC=C32)C4=CC=CS4)S(=O)(=O)C5=CC=CC=C5 |
Product Overview
4-{[4-(Phenylsulfonyl)-1-piperazinyl]carbonyl}-2-(2-thienyl)quinoline (CAS 774575-05-2), with molecular formula C24H21N3O3S2 and molecular weight 463.10 g/mol. IUPAC: [4-(benzenesulfonyl)piperazin-1-yl]-(2-thiophen-2-ylquinolin-4-yl)methanone.
Chemical Property Profile of 4-{[4-(Phenylsulfonyl)-1-piperazinyl]carbonyl}-2-(2-thienyl)quinoline
Property Insights of 4-{[4-(Phenylsulfonyl)-1-piperazinyl]carbonyl}-2-(2-thienyl)quinoline
The XLogP value of 4.11 indicates that 4-{[4-(Phenylsulfonyl)-1-piperazinyl]carbonyl}-2-(2-thienyl)quinoline is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 70.58 Ų falls within the moderate polarity range, balancing permeability and solubility for 4-{[4-(Phenylsulfonyl)-1-piperazinyl]carbonyl}-2-(2-thienyl)quinoline. Following Lipinski's Rule of Five, 4-{[4-(Phenylsulfonyl)-1-piperazinyl]carbonyl}-2-(2-thienyl)quinoline has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-{[4-(Phenylsulfonyl)-1-piperazinyl]carbonyl}-2-(2-thienyl)quinoline?
The CAS number of 4-{[4-(Phenylsulfonyl)-1-piperazinyl]carbonyl}-2-(2-thienyl)quinoline is 774575-05-2.
What is the molecular formula of 4-{[4-(Phenylsulfonyl)-1-piperazinyl]carbonyl}-2-(2-thienyl)quinoline?
The molecular formula of 4-{[4-(Phenylsulfonyl)-1-piperazinyl]carbonyl}-2-(2-thienyl)quinoline is C24H21N3O3S2.
What is the molecular weight of 4-{[4-(Phenylsulfonyl)-1-piperazinyl]carbonyl}-2-(2-thienyl)quinoline?
The molecular weight of 4-{[4-(Phenylsulfonyl)-1-piperazinyl]carbonyl}-2-(2-thienyl)quinoline is 463.10 g/mol.
Where can I buy 4-{[4-(Phenylsulfonyl)-1-piperazinyl]carbonyl}-2-(2-thienyl)quinoline?
You can request a quote for 4-{[4-(Phenylsulfonyl)-1-piperazinyl]carbonyl}-2-(2-thienyl)quinoline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-{[4-(Phenylsulfonyl)-1-piperazinyl]carbonyl}-2-(2-thienyl)quinoline?
Yes, KEHONG BIO provides custom synthesis services for 4-{[4-(Phenylsulfonyl)-1-piperazinyl]carbonyl}-2-(2-thienyl)quinoline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.