1-(2-chloro-6-fluorophenyl)-N-(pyridin-2-ylmethyl)methanamine
TL;DR: 1-(2-chloro-6-fluorophenyl)-N-(pyridin-2-ylmethyl)methanamine (CAS 774555-75-8) is a chemical compound with molecular formula C13H12ClFN2 and molecular weight 250.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[(2-chloro-6-fluorophenyl)methyl]-1-pyridin-2-ylmethanamine
Also Known As: AN-465/42886417, 1-(2-chloro-6-fluorophenyl)-N-(pyridin-2-ylmethyl)methanamine, (2-Chloro-6-fluoro-benzyl)-pyridin-2-ylmethyl-amine, N-(2-chloro-6-fluorobenzyl)-N-(2-pyridinylmethyl)amine, N-[(2-chloro-6-fluorophenyl)methyl]-1-pyridin-2-ylmethanamine
| Molecular Formula | C13H12ClFN2 |
|---|---|
| Molecular Weight | 250.07 g/mol |
| LogP | 3.1639 |
| Topological Polar Surface Area | 24.92 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 4 |
| Exact Mass | 250.0673 |
| Heavy Atoms | 17 |
| Complexity | 467.78305 |
Chemical Identifiers
| CAS Number | 774555-75-8 |
|---|---|
| SMILES | C1=CC=NC(=C1)CNCC2=C(C=CC=C2Cl)F |
Product Overview
1-(2-chloro-6-fluorophenyl)-N-(pyridin-2-ylmethyl)methanamine (CAS 774555-75-8), with molecular formula C13H12ClFN2 and molecular weight 250.07 g/mol. IUPAC: N-[(2-chloro-6-fluorophenyl)methyl]-1-pyridin-2-ylmethanamine.
Chemical Property Profile of 1-(2-chloro-6-fluorophenyl)-N-(pyridin-2-ylmethyl)methanamine
Property Insights of 1-(2-chloro-6-fluorophenyl)-N-(pyridin-2-ylmethyl)methanamine
The XLogP value of 3.1639 indicates that 1-(2-chloro-6-fluorophenyl)-N-(pyridin-2-ylmethyl)methanamine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 24.92 Ų, 1-(2-chloro-6-fluorophenyl)-N-(pyridin-2-ylmethyl)methanamine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-(2-chloro-6-fluorophenyl)-N-(pyridin-2-ylmethyl)methanamine has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-(2-chloro-6-fluorophenyl)-N-(pyridin-2-ylmethyl)methanamine?
The CAS number of 1-(2-chloro-6-fluorophenyl)-N-(pyridin-2-ylmethyl)methanamine is 774555-75-8.
What is the molecular formula of 1-(2-chloro-6-fluorophenyl)-N-(pyridin-2-ylmethyl)methanamine?
The molecular formula of 1-(2-chloro-6-fluorophenyl)-N-(pyridin-2-ylmethyl)methanamine is C13H12ClFN2.
What is the molecular weight of 1-(2-chloro-6-fluorophenyl)-N-(pyridin-2-ylmethyl)methanamine?
The molecular weight of 1-(2-chloro-6-fluorophenyl)-N-(pyridin-2-ylmethyl)methanamine is 250.07 g/mol.
Where can I buy 1-(2-chloro-6-fluorophenyl)-N-(pyridin-2-ylmethyl)methanamine?
You can request a quote for 1-(2-chloro-6-fluorophenyl)-N-(pyridin-2-ylmethyl)methanamine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-(2-chloro-6-fluorophenyl)-N-(pyridin-2-ylmethyl)methanamine?
Yes, KEHONG BIO provides custom synthesis services for 1-(2-chloro-6-fluorophenyl)-N-(pyridin-2-ylmethyl)methanamine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.