![[4-[4-Nitro-2-(trifluoromethyl)phenyl]piperazin-1-yl]-thiophen-2-ylmethanone structure](/static/products/7745/774549-87-0.webp)
[4-[4-Nitro-2-(trifluoromethyl)phenyl]piperazin-1-yl]-thiophen-2-ylmethanone
TL;DR: [4-[4-Nitro-2-(trifluoromethyl)phenyl]piperazin-1-yl]-thiophen-2-ylmethanone (CAS 774549-87-0) is a chemical compound with molecular formula C16H14F3N3O3S and molecular weight 385.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[4-[4-nitro-2-(trifluoromethyl)phenyl]piperazin-1-yl]-thiophen-2-ylmethanone
Also Known As: [4-[4-nitro-2-(trifluoromethyl)phenyl]piperazin-1-yl]-thiophen-2-ylmethanone, {4-[4-nitro-2-(trifluoromethyl)phenyl]piperazin-1-yl}(thiophen-2-yl)methanone
| Molecular Formula | C16H14F3N3O3S |
|---|---|
| Molecular Weight | 385.07 g/mol |
| LogP | 3.6375 |
| Topological Polar Surface Area | 66.69 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Exact Mass | 385.0708 |
| Heavy Atoms | 26 |
| Complexity | 815.88776 |
Chemical Identifiers
| CAS Number | 774549-87-0 |
|---|---|
| SMILES | C1CN(CCN1C2=C(C=C(C=C2)[N+](=O)[O-])C(F)(F)F)C(=O)C3=CC=CS3 |
Product Overview
[4-[4-Nitro-2-(trifluoromethyl)phenyl]piperazin-1-yl]-thiophen-2-ylmethanone (CAS 774549-87-0), with molecular formula C16H14F3N3O3S and molecular weight 385.07 g/mol. IUPAC: [4-[4-nitro-2-(trifluoromethyl)phenyl]piperazin-1-yl]-thiophen-2-ylmethanone.
Chemical Property Profile of [4-[4-Nitro-2-(trifluoromethyl)phenyl]piperazin-1-yl]-thiophen-2-ylmethanone
Property Insights of [4-[4-Nitro-2-(trifluoromethyl)phenyl]piperazin-1-yl]-thiophen-2-ylmethanone
The XLogP value of 3.6375 indicates that [4-[4-Nitro-2-(trifluoromethyl)phenyl]piperazin-1-yl]-thiophen-2-ylmethanone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 66.69 Ų falls within the moderate polarity range, balancing permeability and solubility for [4-[4-Nitro-2-(trifluoromethyl)phenyl]piperazin-1-yl]-thiophen-2-ylmethanone. Following Lipinski's Rule of Five, [4-[4-Nitro-2-(trifluoromethyl)phenyl]piperazin-1-yl]-thiophen-2-ylmethanone has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of [4-[4-Nitro-2-(trifluoromethyl)phenyl]piperazin-1-yl]-thiophen-2-ylmethanone?
The CAS number of [4-[4-Nitro-2-(trifluoromethyl)phenyl]piperazin-1-yl]-thiophen-2-ylmethanone is 774549-87-0.
What is the molecular formula of [4-[4-Nitro-2-(trifluoromethyl)phenyl]piperazin-1-yl]-thiophen-2-ylmethanone?
The molecular formula of [4-[4-Nitro-2-(trifluoromethyl)phenyl]piperazin-1-yl]-thiophen-2-ylmethanone is C16H14F3N3O3S.
What is the molecular weight of [4-[4-Nitro-2-(trifluoromethyl)phenyl]piperazin-1-yl]-thiophen-2-ylmethanone?
The molecular weight of [4-[4-Nitro-2-(trifluoromethyl)phenyl]piperazin-1-yl]-thiophen-2-ylmethanone is 385.07 g/mol.
Where can I buy [4-[4-Nitro-2-(trifluoromethyl)phenyl]piperazin-1-yl]-thiophen-2-ylmethanone?
You can request a quote for [4-[4-Nitro-2-(trifluoromethyl)phenyl]piperazin-1-yl]-thiophen-2-ylmethanone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for [4-[4-Nitro-2-(trifluoromethyl)phenyl]piperazin-1-yl]-thiophen-2-ylmethanone?
Yes, KEHONG BIO provides custom synthesis services for [4-[4-Nitro-2-(trifluoromethyl)phenyl]piperazin-1-yl]-thiophen-2-ylmethanone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.