5-Chloro-4-(4-fluorophenyl)-1,2,3-thiadiazole
TL;DR: 5-Chloro-4-(4-fluorophenyl)-1,2,3-thiadiazole (CAS 77414-44-9) is a chemical compound with molecular formula C8H4ClFN2S and molecular weight 213.98 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-chloro-4-(4-fluorophenyl)thiadiazole
Also Known As: 5-Chloro-4-(4-fluorophenyl)-1,2,3-thiadiazole, chlorofluorophenylthiadiazole, 5-chloro-4-(4-fluorophenyl)thiadiazole, 3H-353S
| Molecular Formula | C8H4ClFN2S |
|---|---|
| Molecular Weight | 213.98 g/mol |
| LogP | 2.9976 |
| Topological Polar Surface Area | 25.78 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 213.97678 |
| Heavy Atoms | 13 |
| Complexity | 412.3373 |
Chemical Identifiers
| CAS Number | 77414-44-9 |
|---|---|
| SMILES | C1=CC(=CC=C1C2=C(SN=N2)Cl)F |
Product Overview
5-Chloro-4-(4-fluorophenyl)-1,2,3-thiadiazole (CAS 77414-44-9), with molecular formula C8H4ClFN2S and molecular weight 213.98 g/mol. IUPAC: 5-chloro-4-(4-fluorophenyl)thiadiazole.
Chemical Property Profile of 5-Chloro-4-(4-fluorophenyl)-1,2,3-thiadiazole
Property Insights of 5-Chloro-4-(4-fluorophenyl)-1,2,3-thiadiazole
The XLogP value of 2.9976 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 5-Chloro-4-(4-fluorophenyl)-1,2,3-thiadiazole. With a topological polar surface area (TPSA) of 25.78 Ų, 5-Chloro-4-(4-fluorophenyl)-1,2,3-thiadiazole exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5-Chloro-4-(4-fluorophenyl)-1,2,3-thiadiazole has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-Chloro-4-(4-fluorophenyl)-1,2,3-thiadiazole?
The CAS number of 5-Chloro-4-(4-fluorophenyl)-1,2,3-thiadiazole is 77414-44-9.
What is the molecular formula of 5-Chloro-4-(4-fluorophenyl)-1,2,3-thiadiazole?
The molecular formula of 5-Chloro-4-(4-fluorophenyl)-1,2,3-thiadiazole is C8H4ClFN2S.
What is the molecular weight of 5-Chloro-4-(4-fluorophenyl)-1,2,3-thiadiazole?
The molecular weight of 5-Chloro-4-(4-fluorophenyl)-1,2,3-thiadiazole is 213.98 g/mol.
Where can I buy 5-Chloro-4-(4-fluorophenyl)-1,2,3-thiadiazole?
You can request a quote for 5-Chloro-4-(4-fluorophenyl)-1,2,3-thiadiazole directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-Chloro-4-(4-fluorophenyl)-1,2,3-thiadiazole?
Yes, KEHONG BIO provides custom synthesis services for 5-Chloro-4-(4-fluorophenyl)-1,2,3-thiadiazole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.