2-Chloro-1-(4-chlorophenyl)-2,2-difluoroethanone
TL;DR: 2-Chloro-1-(4-chlorophenyl)-2,2-difluoroethanone (CAS 774-29-8) is a chemical compound with molecular formula C8H4Cl2F2O and molecular weight 223.96 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-chloro-1-(4-chlorophenyl)-2,2-difluoroethanone
Also Known As: 2-chloro-1-(4-chlorophenyl)-2,2-difluoroethanone, 2-Chloro-1-(4-chlorophenyl)-2,2-difluoro-ethanone, 7-fluoro-3,4-dihydro-2H-benzo[b]oxepin-5-one, 2-Chloro-1-(4-chloro-phenyl)-2,2-difluoro-ethanone, 2-Chloro-1-(4-chlorophenyl)-2,2-difluoroethan-1-one
| Molecular Formula | C8H4Cl2F2O |
|---|---|
| Molecular Weight | 223.96 g/mol |
| LogP | 3.6 |
| Topological Polar Surface Area | 17.1 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 223.96072 |
| Heavy Atoms | 13 |
| Complexity | 200.0 |
Chemical Identifiers
| CAS Number | 774-29-8 |
|---|---|
| SMILES | C1=CC(=CC=C1C(=O)C(F)(F)Cl)Cl |
| InChIKey | ZMCFDDNVCUMJHA-UHFFFAOYSA-N |
Product Overview
2-Chloro-1-(4-chlorophenyl)-2,2-difluoroethanone (CAS 774-29-8), with molecular formula C8H4Cl2F2O and molecular weight 223.96 g/mol. IUPAC: 2-chloro-1-(4-chlorophenyl)-2,2-difluoroethanone.
Chemical Property Profile of 2-Chloro-1-(4-chlorophenyl)-2,2-difluoroethanone
Property Insights of 2-Chloro-1-(4-chlorophenyl)-2,2-difluoroethanone
The XLogP value of 3.6 indicates that 2-Chloro-1-(4-chlorophenyl)-2,2-difluoroethanone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 17.1 Ų, 2-Chloro-1-(4-chlorophenyl)-2,2-difluoroethanone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-Chloro-1-(4-chlorophenyl)-2,2-difluoroethanone has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-Chloro-1-(4-chlorophenyl)-2,2-difluoroethanone?
The CAS number of 2-Chloro-1-(4-chlorophenyl)-2,2-difluoroethanone is 774-29-8.
What is the molecular formula of 2-Chloro-1-(4-chlorophenyl)-2,2-difluoroethanone?
The molecular formula of 2-Chloro-1-(4-chlorophenyl)-2,2-difluoroethanone is C8H4Cl2F2O.
What is the molecular weight of 2-Chloro-1-(4-chlorophenyl)-2,2-difluoroethanone?
The molecular weight of 2-Chloro-1-(4-chlorophenyl)-2,2-difluoroethanone is 223.96 g/mol.
Where can I buy 2-Chloro-1-(4-chlorophenyl)-2,2-difluoroethanone?
You can request a quote for 2-Chloro-1-(4-chlorophenyl)-2,2-difluoroethanone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-Chloro-1-(4-chlorophenyl)-2,2-difluoroethanone?
Yes, KEHONG BIO provides custom synthesis services for 2-Chloro-1-(4-chlorophenyl)-2,2-difluoroethanone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.