![n-[Butyl(dimethyl)silyl]-2,2,2-trifluoro-n-methylacetamide structure](/static/products/7737/77377-52-7.webp)
n-[Butyl(dimethyl)silyl]-2,2,2-trifluoro-n-methylacetamide
TL;DR: n-[Butyl(dimethyl)silyl]-2,2,2-trifluoro-n-methylacetamide (CAS 77377-52-7) is a chemical compound with molecular formula C9H18F3NOSi and molecular weight 241.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[butyl(dimethyl)silyl]-2,2,2-trifluoro-N-methylacetamide
Also Known As: Mtbstfa, n-[butyl(dimethyl)silyl]-2,2,2-trifluoro-n-methylacetamide, I14-6674, n-(tert-butyldimethylsilyl)-n-methyl trifluoroacetamide, n-(tert-butyldimethylsilyl)-n-methyl-trifluoroacetamide
| Molecular Formula | C9H18F3NOSi |
|---|---|
| Molecular Weight | 241.11 g/mol |
| LogP | 3.01 |
| Topological Polar Surface Area | 20.3 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 241.11098 |
| Heavy Atoms | 15 |
| Complexity | 228.0 |
Chemical Identifiers
| CAS Number | 77377-52-7 |
|---|---|
| SMILES | CCCC[Si](C)(C)N(C)C(=O)C(F)(F)F |
| InChIKey | NEJIKZHUEMMAEF-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
n-[Butyl(dimethyl)silyl]-2,2,2-trifluoro-n-methylacetamide (CAS 77377-52-7), with molecular formula C9H18F3NOSi and molecular weight 241.11 g/mol. IUPAC: N-[butyl(dimethyl)silyl]-2,2,2-trifluoro-N-methylacetamide.
Chemical Property Profile of n-[Butyl(dimethyl)silyl]-2,2,2-trifluoro-n-methylacetamide
Property Insights of n-[Butyl(dimethyl)silyl]-2,2,2-trifluoro-n-methylacetamide
The XLogP value of 3.01 indicates that n-[Butyl(dimethyl)silyl]-2,2,2-trifluoro-n-methylacetamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 20.3 Ų, n-[Butyl(dimethyl)silyl]-2,2,2-trifluoro-n-methylacetamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, n-[Butyl(dimethyl)silyl]-2,2,2-trifluoro-n-methylacetamide has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of n-[Butyl(dimethyl)silyl]-2,2,2-trifluoro-n-methylacetamide?
The CAS number of n-[Butyl(dimethyl)silyl]-2,2,2-trifluoro-n-methylacetamide is 77377-52-7.
What is the molecular formula of n-[Butyl(dimethyl)silyl]-2,2,2-trifluoro-n-methylacetamide?
The molecular formula of n-[Butyl(dimethyl)silyl]-2,2,2-trifluoro-n-methylacetamide is C9H18F3NOSi.
What is the molecular weight of n-[Butyl(dimethyl)silyl]-2,2,2-trifluoro-n-methylacetamide?
The molecular weight of n-[Butyl(dimethyl)silyl]-2,2,2-trifluoro-n-methylacetamide is 241.11 g/mol.
Where can I buy n-[Butyl(dimethyl)silyl]-2,2,2-trifluoro-n-methylacetamide?
You can request a quote for n-[Butyl(dimethyl)silyl]-2,2,2-trifluoro-n-methylacetamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for n-[Butyl(dimethyl)silyl]-2,2,2-trifluoro-n-methylacetamide?
Yes, KEHONG BIO provides custom synthesis services for n-[Butyl(dimethyl)silyl]-2,2,2-trifluoro-n-methylacetamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.