Ethyl 4-phenyl-2-((2-(1-piperidinyl)acetyl)amino)-3-thiophenecarboxylate structure

Ethyl 4-phenyl-2-((2-(1-piperidinyl)acetyl)amino)-3-thiophenecarboxylate

TL;DR: Ethyl 4-phenyl-2-((2-(1-piperidinyl)acetyl)amino)-3-thiophenecarboxylate (CAS 77261-22-4) is a chemical compound with molecular formula C20H24N2O3S and molecular weight 372.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

ethyl 4-phenyl-2-[(2-piperidin-1-ylacetyl)amino]thiophene-3-carboxylate

Also Known As: 3-Thiophenecarboxylic acid, 4-phenyl-2-((1-piperidinylacetyl)amino)-, ethyl ester, Ethyl 4-phenyl-2-(2-(piperidin-1-yl)acetamido)thiophene-3-carboxylate, ethyl 4-phenyl-2-[(piperidin-1-ylacetyl)amino]thiophene-3-carboxylate, AE-848/33844033, Ethyl 4-phenyl-2-((1-piperidinylacetyl)amino)-3-thiophenecarboxylate

CAS: 77261-22-4
Molecular Formula C20H24N2O3S
Molecular Weight 372.15 g/mol
LogP 4.4
Topological Polar Surface Area 86.9 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 5
Rotatable Bonds 7
Exact Mass 372.15076
Heavy Atoms 26
Complexity 476.0

Chemical Identifiers

CAS Number 77261-22-4
SMILES CCOC(=O)C1=C(SC=C1C2=CC=CC=C2)NC(=O)CN3CCCCC3
InChIKey RCSIOWHXZCAOBL-UHFFFAOYSA-N

Product Overview

Ethyl 4-phenyl-2-((2-(1-piperidinyl)acetyl)amino)-3-thiophenecarboxylate (CAS 77261-22-4), with molecular formula C20H24N2O3S and molecular weight 372.15 g/mol. IUPAC: ethyl 4-phenyl-2-[(2-piperidin-1-ylacetyl)amino]thiophene-3-carboxylate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of Ethyl 4-phenyl-2-((2-(1-piperidinyl)acetyl)amino)-3-thiophenecarboxylate

XLogP
4.4
TPSA (Topological Polar Surface Area)
86.9
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
5
Rotatable Bonds
7
Heavy Atoms
26
Complexity
476.0
Exact Mass
372.15076
Monoisotopic Mass
372.15076
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Ethyl 4-phenyl-2-((2-(1-piperidinyl)acetyl)amino)-3-thiophenecarboxylate

The XLogP value of 4.4 indicates that Ethyl 4-phenyl-2-((2-(1-piperidinyl)acetyl)amino)-3-thiophenecarboxylate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 86.9 Ų falls within the moderate polarity range, balancing permeability and solubility for Ethyl 4-phenyl-2-((2-(1-piperidinyl)acetyl)amino)-3-thiophenecarboxylate. Following Lipinski's Rule of Five, Ethyl 4-phenyl-2-((2-(1-piperidinyl)acetyl)amino)-3-thiophenecarboxylate has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Ethyl 4-phenyl-2-((2-(1-piperidinyl)acetyl)amino)-3-thiophenecarboxylate?

The CAS number of Ethyl 4-phenyl-2-((2-(1-piperidinyl)acetyl)amino)-3-thiophenecarboxylate is 77261-22-4.

What is the molecular formula of Ethyl 4-phenyl-2-((2-(1-piperidinyl)acetyl)amino)-3-thiophenecarboxylate?

The molecular formula of Ethyl 4-phenyl-2-((2-(1-piperidinyl)acetyl)amino)-3-thiophenecarboxylate is C20H24N2O3S.

What is the molecular weight of Ethyl 4-phenyl-2-((2-(1-piperidinyl)acetyl)amino)-3-thiophenecarboxylate?

The molecular weight of Ethyl 4-phenyl-2-((2-(1-piperidinyl)acetyl)amino)-3-thiophenecarboxylate is 372.15 g/mol.

Where can I buy Ethyl 4-phenyl-2-((2-(1-piperidinyl)acetyl)amino)-3-thiophenecarboxylate?

You can request a quote for Ethyl 4-phenyl-2-((2-(1-piperidinyl)acetyl)amino)-3-thiophenecarboxylate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Ethyl 4-phenyl-2-((2-(1-piperidinyl)acetyl)amino)-3-thiophenecarboxylate?

Yes, KEHONG BIO provides custom synthesis services for Ethyl 4-phenyl-2-((2-(1-piperidinyl)acetyl)amino)-3-thiophenecarboxylate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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