2,2,2-Trifluoro-N'-(trifluoroacetyl)acetohydrazide
TL;DR: 2,2,2-Trifluoro-N'-(trifluoroacetyl)acetohydrazide (CAS 77244-88-3) is a chemical compound with molecular formula C4H2F6N2O2 and molecular weight 224.00 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2,2,2-trifluoro-N'-(2,2,2-trifluoroacetyl)acetohydrazide
Also Known As: 2,2,2-Trifluoro-N'-(trifluoroacetyl)acetohydrazide, 2,2,2-trifluoro-n'-(2,2,2-trifluoroacetyl)acetohydrazide, Sitagliptin Impurity 58, di(trifluoroacetyl)hydrazine, 1,2-bis(trifluoroacetyl)hydrazine
| Molecular Formula | C4H2F6N2O2 |
|---|---|
| Molecular Weight | 224.00 g/mol |
| LogP | 1.3 |
| Topological Polar Surface Area | 58.2 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 0 |
| Exact Mass | 224.00204 |
| Heavy Atoms | 14 |
| Complexity | 217.0 |
Chemical Identifiers
| CAS Number | 77244-88-3 |
|---|---|
| SMILES | C(=O)(C(F)(F)F)NNC(=O)C(F)(F)F |
| InChIKey | UNVFMKVRYRCPIS-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
2,2,2-Trifluoro-N'-(trifluoroacetyl)acetohydrazide (CAS 77244-88-3), with molecular formula C4H2F6N2O2 and molecular weight 224.00 g/mol. IUPAC: 2,2,2-trifluoro-N'-(2,2,2-trifluoroacetyl)acetohydrazide.
Chemical Property Profile of 2,2,2-Trifluoro-N'-(trifluoroacetyl)acetohydrazide
Property Insights of 2,2,2-Trifluoro-N'-(trifluoroacetyl)acetohydrazide
The XLogP value of 1.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2,2,2-Trifluoro-N'-(trifluoroacetyl)acetohydrazide. With a topological polar surface area (TPSA) of 58.2 Ų, 2,2,2-Trifluoro-N'-(trifluoroacetyl)acetohydrazide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2,2,2-Trifluoro-N'-(trifluoroacetyl)acetohydrazide has 2 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2,2,2-Trifluoro-N'-(trifluoroacetyl)acetohydrazide?
The CAS number of 2,2,2-Trifluoro-N'-(trifluoroacetyl)acetohydrazide is 77244-88-3.
What is the molecular formula of 2,2,2-Trifluoro-N'-(trifluoroacetyl)acetohydrazide?
The molecular formula of 2,2,2-Trifluoro-N'-(trifluoroacetyl)acetohydrazide is C4H2F6N2O2.
What is the molecular weight of 2,2,2-Trifluoro-N'-(trifluoroacetyl)acetohydrazide?
The molecular weight of 2,2,2-Trifluoro-N'-(trifluoroacetyl)acetohydrazide is 224.00 g/mol.
Where can I buy 2,2,2-Trifluoro-N'-(trifluoroacetyl)acetohydrazide?
You can request a quote for 2,2,2-Trifluoro-N'-(trifluoroacetyl)acetohydrazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2,2,2-Trifluoro-N'-(trifluoroacetyl)acetohydrazide?
Yes, KEHONG BIO provides custom synthesis services for 2,2,2-Trifluoro-N'-(trifluoroacetyl)acetohydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.