Cyclo(trp-lys-thr-phe-pro-phe)acetate structure

Cyclo(trp-lys-thr-phe-pro-phe)acetate

TL;DR: Cyclo(trp-lys-thr-phe-pro-phe)acetate (CAS 77236-35-2) is a chemical compound with molecular formula C44H54N8O7 and molecular weight 806.41 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(2S)-1-[(2S)-2-[[(2S,3R)-2-[[(2S)-2,6-diaminohexanoyl]amino]-3-hydroxybutanoyl]amino]-3-phenylpropanoyl]-N-[(2S)-1-[[(2R)-1-(1H-indol-3-yl)-3-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]-2,5-dihydropyrrole-2-carboxamide

Also Known As: Cyclo(trp-lys-thr-phe-pro-phe)acetate, L 363568, L-363,568, (2S)-1-[(2S)-2-[[(2S,3R)-2-[[(2S)-2,6-diaminohexanoyl]amino]-3-hydroxybutanoyl]amino]-3-phenylpropanoyl]-N-[(2S)-1-[[(2R)-1-(1H-indol-3-yl)-3-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]-2,5-dihydropyrrole-2-carboxamide, Cyclo(L-lysyl-L-threonyl-L-phenylalanyl-L-prolyl-L-phenylalanyl-D-tryptophyl)

CAS: 77236-35-2
Molecular Formula C44H54N8O7
Molecular Weight 806.41 g/mol
LogP 2.2
Topological Polar Surface Area 242.0 Ų
Hydrogen Bond Donors 8
Hydrogen Bond Acceptors 9
Rotatable Bonds 21
Exact Mass 806.41156
Heavy Atoms 59
Complexity 1440.0

Chemical Identifiers

CAS Number 77236-35-2
SMILES C[C@H]([C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N2CC=C[C@H]2C(=O)N[C@@H](CC3=CC=CC=C3)C(=O)N[C@H](CC4=CNC5=CC=CC=C54)C=O)NC(=O)[C@H](CCCCN)N)O
InChIKey WNFMQQRLCXKKFH-FRAGMDTNSA-N

Product Overview

Cyclo(trp-lys-thr-phe-pro-phe)acetate (CAS 77236-35-2), with molecular formula C44H54N8O7 and molecular weight 806.41 g/mol. IUPAC: (2S)-1-[(2S)-2-[[(2S,3R)-2-[[(2S)-2,6-diaminohexanoyl]amino]-3-hydroxybutanoyl]amino]-3-phenylpropanoyl]-N-[(2S)-1-[[(2R)-1-(1H-indol-3-yl)-3-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]-2,5-dihydropyrrole-2-carboxamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Cyclo(trp-lys-thr-phe-pro-phe)acetate

XLogP
2.2
TPSA (Topological Polar Surface Area)
242.0
Hydrogen Bond Donors
8
Hydrogen Bond Acceptors
9
Rotatable Bonds
21
Heavy Atoms
59
Complexity
1440.0
Exact Mass
806.41156
Monoisotopic Mass
806.41156
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Cyclo(trp-lys-thr-phe-pro-phe)acetate

The XLogP value of 2.2 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Cyclo(trp-lys-thr-phe-pro-phe)acetate. The TPSA of 242.0 Ų indicates high polarity, suggesting Cyclo(trp-lys-thr-phe-pro-phe)acetate may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Cyclo(trp-lys-thr-phe-pro-phe)acetate has 8 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Cyclo(trp-lys-thr-phe-pro-phe)acetate?

The CAS number of Cyclo(trp-lys-thr-phe-pro-phe)acetate is 77236-35-2.

What is the molecular formula of Cyclo(trp-lys-thr-phe-pro-phe)acetate?

The molecular formula of Cyclo(trp-lys-thr-phe-pro-phe)acetate is C44H54N8O7.

What is the molecular weight of Cyclo(trp-lys-thr-phe-pro-phe)acetate?

The molecular weight of Cyclo(trp-lys-thr-phe-pro-phe)acetate is 806.41 g/mol.

Where can I buy Cyclo(trp-lys-thr-phe-pro-phe)acetate?

You can request a quote for Cyclo(trp-lys-thr-phe-pro-phe)acetate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Cyclo(trp-lys-thr-phe-pro-phe)acetate?

Yes, KEHONG BIO provides custom synthesis services for Cyclo(trp-lys-thr-phe-pro-phe)acetate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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