L-5-Fluorouridine
TL;DR: L-5-Fluorouridine (CAS 77210-26-5) is a chemical compound with molecular formula C9H11FN2O6 and molecular weight 262.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[(2S,3S,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-fluoropyrimidine-2,4-dione
Also Known As: L-5-Fluorouridine, beta-L-5FU, 5-Fluorouracil arabinoside, 1-beta-L-Ribofuranosyl-5-fluorouracil, 5-Fluoro-1-(b-L-ribofuranosyl)-uracil
| Molecular Formula | C9H11FN2O6 |
|---|---|
| Molecular Weight | 262.06 g/mol |
| LogP | -2.7128 |
| Topological Polar Surface Area | 124.78 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 2 |
| Exact Mass | 262.06012 |
| Heavy Atoms | 18 |
| Complexity | 554.72424 |
Chemical Identifiers
| CAS Number | 77210-26-5 |
|---|---|
| SMILES | C1=C(C(=O)NC(=O)N1[C@@H]2[C@H]([C@H]([C@@H](O2)CO)O)O)F |
Product Overview
L-5-Fluorouridine (CAS 77210-26-5), with molecular formula C9H11FN2O6 and molecular weight 262.06 g/mol. IUPAC: 1-[(2S,3S,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-fluoropyrimidine-2,4-dione.
Chemical Property Profile of L-5-Fluorouridine
Property Insights of L-5-Fluorouridine
The XLogP value of -2.7128 indicates that L-5-Fluorouridine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 124.78 Ų falls within the moderate polarity range, balancing permeability and solubility for L-5-Fluorouridine. Following Lipinski's Rule of Five, L-5-Fluorouridine has 4 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of L-5-Fluorouridine?
The CAS number of L-5-Fluorouridine is 77210-26-5.
What is the molecular formula of L-5-Fluorouridine?
The molecular formula of L-5-Fluorouridine is C9H11FN2O6.
What is the molecular weight of L-5-Fluorouridine?
The molecular weight of L-5-Fluorouridine is 262.06 g/mol.
Where can I buy L-5-Fluorouridine?
You can request a quote for L-5-Fluorouridine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for L-5-Fluorouridine?
Yes, KEHONG BIO provides custom synthesis services for L-5-Fluorouridine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.