Fluorescein-thyrotropin-releasing hormone
TL;DR: Fluorescein-thyrotropin-releasing hormone (CAS 77160-98-6) is a chemical compound with molecular formula C43H46N8O9S and molecular weight 850.31 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2S)-N-[(2S)-1-[[(2S)-1-[6-[(3',6'-dihydroxy-3-oxospiro[2-benzofuran-1,9'-xanthene]-5-yl)carbamothioylamino]hexyl]pyrrolidine-2-carbonyl]amino]-3-(4H-imidazol-4-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
Also Known As: Fl-Trh, Fluorescein-thyrotropin-releasing hormone, (2S)-N-[(2S)-1-[[(2S)-1-[6-[(3',6'-dihydroxy-3-oxospiro[2-benzofuran-1,9'-xanthene]-5-yl)carbamothioylamino]hexyl]pyrrolidine-2-carbonyl]amino]-3-(4H-imidazol-4-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide, L-Prolinamide, 5-oxo-L-prolyl-L-histidyl-N-(6-((((3',6'-dihydroxy-3-oxospiro(isobenzofuran-1(3H),9'-(9H)xanthen)-5-yl)amino)thioxomethyl)amino)hexyl)-, (2S)-N-[(2S)-1-({1-[6-({[(3',6'-Dihydroxy-3-oxo-3H-spiro[[2]benzofuran-1,9'-xanthen]-5-yl)amino](sulfanyl)methylidene}amino)hexyl]-L-prolyl}imino)-1-hydroxy-3-(4H-imidazol-4-yl)propan-2-yl]-5-hydroxy-3,4-dihydro-2H-pyrrole-2-carboximidic acid
| Molecular Formula | C43H46N8O9S |
|---|---|
| Molecular Weight | 850.31 g/mol |
| LogP | 3.2546 |
| Topological Polar Surface Area | 232.38 Ų |
| Hydrogen Bond Donors | 7 |
| Hydrogen Bond Acceptors | 13 |
| Rotatable Bonds | 14 |
| Exact Mass | 850.31085 |
| Heavy Atoms | 61 |
| Complexity | 2272.1917 |
Chemical Identifiers
| CAS Number | 77160-98-6 |
|---|---|
| SMILES | C1C[C@H](N(C1)CCCCCCNC(=S)NC2=CC3=C(C=C2)C4(C5=C(C=C(C=C5)O)OC6=C4C=CC(=C6)O)OC3=O)C(=O)NC(=O)[C@H](CC7C=NC=N7)NC(=O)[C@@H]8CCC(=O)N8 |
Product Overview
Fluorescein-thyrotropin-releasing hormone (CAS 77160-98-6), with molecular formula C43H46N8O9S and molecular weight 850.31 g/mol. IUPAC: (2S)-N-[(2S)-1-[[(2S)-1-[6-[(3',6'-dihydroxy-3-oxospiro[2-benzofuran-1,9'-xanthene]-5-yl)carbamothioylamino]hexyl]pyrrolidine-2-carbonyl]amino]-3-(4H-imidazol-4-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide.
Chemical Property Profile of Fluorescein-thyrotropin-releasing hormone
Property Insights of Fluorescein-thyrotropin-releasing hormone
The XLogP value of 3.2546 indicates that Fluorescein-thyrotropin-releasing hormone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 232.38 Ų indicates high polarity, suggesting Fluorescein-thyrotropin-releasing hormone may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Fluorescein-thyrotropin-releasing hormone has 7 hydrogen bond donor(s) and 13 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Fluorescein-thyrotropin-releasing hormone?
The CAS number of Fluorescein-thyrotropin-releasing hormone is 77160-98-6.
What is the molecular formula of Fluorescein-thyrotropin-releasing hormone?
The molecular formula of Fluorescein-thyrotropin-releasing hormone is C43H46N8O9S.
What is the molecular weight of Fluorescein-thyrotropin-releasing hormone?
The molecular weight of Fluorescein-thyrotropin-releasing hormone is 850.31 g/mol.
Where can I buy Fluorescein-thyrotropin-releasing hormone?
You can request a quote for Fluorescein-thyrotropin-releasing hormone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Fluorescein-thyrotropin-releasing hormone?
Yes, KEHONG BIO provides custom synthesis services for Fluorescein-thyrotropin-releasing hormone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.