Dihydrorotenone
TL;DR: Dihydrorotenone (CAS 77156-75-3) is a chemical compound with molecular formula C23H24O6 and molecular weight 396.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(1S,6R,13S)-16,17-dimethoxy-6-propan-2-yl-2,7,20-trioxapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),9,14,16,18-hexaen-12-one
Also Known As: Dihydrorotenone, 1',2'-Dihydrorotenone, S,S-Dihydrorotenone, Rotenone, dihydro-, 6',7'-Dihydrorotenone
| Molecular Formula | C23H24O6 |
|---|---|
| Molecular Weight | 396.16 g/mol |
| LogP | 4.2 |
| Topological Polar Surface Area | 63.2 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 3 |
| Exact Mass | 396.1573 |
| Heavy Atoms | 29 |
| Complexity | 622.0 |
Chemical Identifiers
| CAS Number | 77156-75-3 |
|---|---|
| SMILES | CC(C)[C@H]1CC2=C(O1)C=CC3=C2O[C@@H]4COC5=CC(=C(C=C5[C@@H]4C3=O)OC)OC |
| InChIKey | DTFARBHXORYQBF-HBGVWJBISA-N |
Product Overview
Dihydrorotenone (CAS 77156-75-3), with molecular formula C23H24O6 and molecular weight 396.16 g/mol. IUPAC: (1S,6R,13S)-16,17-dimethoxy-6-propan-2-yl-2,7,20-trioxapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),9,14,16,18-hexaen-12-one.
Chemical Property Profile of Dihydrorotenone
Property Insights of Dihydrorotenone
The XLogP value of 4.2 indicates that Dihydrorotenone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 63.2 Ų falls within the moderate polarity range, balancing permeability and solubility for Dihydrorotenone. Following Lipinski's Rule of Five, Dihydrorotenone has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Dihydrorotenone?
The CAS number of Dihydrorotenone is 77156-75-3.
What is the molecular formula of Dihydrorotenone?
The molecular formula of Dihydrorotenone is C23H24O6.
What is the molecular weight of Dihydrorotenone?
The molecular weight of Dihydrorotenone is 396.16 g/mol.
Where can I buy Dihydrorotenone?
You can request a quote for Dihydrorotenone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Dihydrorotenone?
Yes, KEHONG BIO provides custom synthesis services for Dihydrorotenone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.