酪氨酰-脯氨酰-亮氨酰-甘氨酰胺 structure

酪氨酰-脯氨酰-亮氨酰-甘氨酰胺

TL;DR: 酪氨酰-脯氨酰-亮氨酰-甘氨酰胺 (CAS 77133-61-0) is a chemical compound with molecular formula C22H33N5O5 and molecular weight 447.25 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

酪氨酰-脯氨酰-亮氨酰-甘氨酰胺

(2S)-1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxohexan-2-yl]pyrrolidine-2-carboxamide

Also Known As: Tyr-mif-1, N-Tyr-mif-1, Tyr-pro-leu-gly-NH2, Tyrosyl-prolyl-leucyl-glycinamide, Tyr-MIF-I, (Tyr0)-MIF-I

CAS: 77133-61-0
Molecular Formula C22H33N5O5
Molecular Weight 447.25 g/mol
LogP 0.1
Topological Polar Surface Area 168.0 Ų
Hydrogen Bond Donors 5
Hydrogen Bond Acceptors 6
Rotatable Bonds 11
Exact Mass 447.24817
Heavy Atoms 32
Complexity 665.0

Chemical Identifiers

CAS Number 77133-61-0
SMILES CCCC[C@@H](C(=O)NCC(=O)N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC2=CC=C(C=C2)O)N
InChIKey SEAGUNDLDLZLLQ-BZSNNMDCSA-N

Product Overview

酪氨酰-脯氨酰-亮氨酰-甘氨酰胺 (CAS 77133-61-0), with molecular formula C22H33N5O5 and molecular weight 447.25 g/mol. IUPAC: (2S)-1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxohexan-2-yl]pyrrolidine-2-carboxamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 酪氨酰-脯氨酰-亮氨酰-甘氨酰胺

XLogP
0.1
TPSA (Topological Polar Surface Area)
168.0
Hydrogen Bond Donors
5
Hydrogen Bond Acceptors
6
Rotatable Bonds
11
Heavy Atoms
32
Complexity
665.0
Exact Mass
447.24817
Monoisotopic Mass
447.24817
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 酪氨酰-脯氨酰-亮氨酰-甘氨酰胺

The XLogP value of 0.1 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 酪氨酰-脯氨酰-亮氨酰-甘氨酰胺. The TPSA of 168.0 Ų indicates high polarity, suggesting 酪氨酰-脯氨酰-亮氨酰-甘氨酰胺 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 酪氨酰-脯氨酰-亮氨酰-甘氨酰胺 has 5 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 酪氨酰-脯氨酰-亮氨酰-甘氨酰胺?

The CAS number of 酪氨酰-脯氨酰-亮氨酰-甘氨酰胺 is 77133-61-0.

What is the molecular formula of 酪氨酰-脯氨酰-亮氨酰-甘氨酰胺?

The molecular formula of 酪氨酰-脯氨酰-亮氨酰-甘氨酰胺 is C22H33N5O5.

What is the molecular weight of 酪氨酰-脯氨酰-亮氨酰-甘氨酰胺?

The molecular weight of 酪氨酰-脯氨酰-亮氨酰-甘氨酰胺 is 447.25 g/mol.

Where can I buy 酪氨酰-脯氨酰-亮氨酰-甘氨酰胺?

You can request a quote for 酪氨酰-脯氨酰-亮氨酰-甘氨酰胺 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 酪氨酰-脯氨酰-亮氨酰-甘氨酰胺?

Yes, KEHONG BIO provides custom synthesis services for 酪氨酰-脯氨酰-亮氨酰-甘氨酰胺 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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