2-Chloro-5-trifluoroacetylthiophene
TL;DR: 2-Chloro-5-trifluoroacetylthiophene (CAS 771-83-5) is a chemical compound with molecular formula C6H2ClF3OS and molecular weight 213.95 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-(5-chlorothiophen-2-yl)-2,2,2-trifluoroethanone
Also Known As: 2-Chloro-5-trifluoroacetylthiophene, 1-(5-chlorothiophen-2-yl)-2,2,2-trifluoroethanone, 1-(5-chlorothiophen-2-yl)-2,2,2-trifluoroethan-1-one, 1-(5-Chloro-2-thienyl)-2,2,2-trifluoroethanone, 5-Chloro-2-(2,2,2-trifluoroacetyl)thiophene
| Molecular Formula | C6H2ClF3OS |
|---|---|
| Molecular Weight | 213.95 g/mol |
| LogP | 3.1465 |
| Topological Polar Surface Area | 17.07 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 213.9467 |
| Heavy Atoms | 12 |
| Complexity | 303.987 |
Chemical Identifiers
| CAS Number | 771-83-5 |
|---|---|
| SMILES | C1=C(SC(=C1)Cl)C(=O)C(F)(F)F |
Product Overview
2-Chloro-5-trifluoroacetylthiophene (CAS 771-83-5), with molecular formula C6H2ClF3OS and molecular weight 213.95 g/mol. IUPAC: 1-(5-chlorothiophen-2-yl)-2,2,2-trifluoroethanone.
Chemical Property Profile of 2-Chloro-5-trifluoroacetylthiophene
Property Insights of 2-Chloro-5-trifluoroacetylthiophene
The XLogP value of 3.1465 indicates that 2-Chloro-5-trifluoroacetylthiophene is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 17.07 Ų, 2-Chloro-5-trifluoroacetylthiophene exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-Chloro-5-trifluoroacetylthiophene has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-Chloro-5-trifluoroacetylthiophene?
The CAS number of 2-Chloro-5-trifluoroacetylthiophene is 771-83-5.
What is the molecular formula of 2-Chloro-5-trifluoroacetylthiophene?
The molecular formula of 2-Chloro-5-trifluoroacetylthiophene is C6H2ClF3OS.
What is the molecular weight of 2-Chloro-5-trifluoroacetylthiophene?
The molecular weight of 2-Chloro-5-trifluoroacetylthiophene is 213.95 g/mol.
Where can I buy 2-Chloro-5-trifluoroacetylthiophene?
You can request a quote for 2-Chloro-5-trifluoroacetylthiophene directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-Chloro-5-trifluoroacetylthiophene?
Yes, KEHONG BIO provides custom synthesis services for 2-Chloro-5-trifluoroacetylthiophene and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.