Colkhisin
TL;DR: Colkhisin (CAS 77096-41-4) is a chemical compound with molecular formula C28H37N3O7 and molecular weight 527.26 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2R)-6-[(7-acetamido-1,2,3-trimethoxy-9-oxo-6,8-dihydro-5H-benzo[a]heptalen-10-yl)methylamino]-2-aminohexanoic acid
Also Known As: Colkhisin, Colchizin, Benzo(a)heptalene, L-lysine deriv., Benzo[a]heptalene, L-lysine deriv., Benzo(a)heptalene, L-lysine deriv. (9CI)
| Molecular Formula | C28H37N3O7 |
|---|---|
| Molecular Weight | 527.26 g/mol |
| LogP | -0.9 |
| Topological Polar Surface Area | 149.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 12 |
| Exact Mass | 527.2631 |
| Heavy Atoms | 38 |
| Complexity | 973.0 |
Chemical Identifiers
| CAS Number | 77096-41-4 |
|---|---|
| SMILES | CC(=O)NC1=C2CC(=O)C(=CC=C2C3=C(C(=C(C=C3CC1)OC)OC)OC)CNCCCC[C@H](C(=O)O)N |
| InChIKey | NRUWROYMQPJMPZ-OAQYLSRUSA-N |
Product Overview
Colkhisin (CAS 77096-41-4), with molecular formula C28H37N3O7 and molecular weight 527.26 g/mol. IUPAC: (2R)-6-[(7-acetamido-1,2,3-trimethoxy-9-oxo-6,8-dihydro-5H-benzo[a]heptalen-10-yl)methylamino]-2-aminohexanoic acid.
Chemical Property Profile of Colkhisin
Property Insights of Colkhisin
The XLogP value of -0.9 indicates that Colkhisin is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 149.0 Ų indicates high polarity, suggesting Colkhisin may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Colkhisin has 4 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Colkhisin?
The CAS number of Colkhisin is 77096-41-4.
What is the molecular formula of Colkhisin?
The molecular formula of Colkhisin is C28H37N3O7.
What is the molecular weight of Colkhisin?
The molecular weight of Colkhisin is 527.26 g/mol.
Where can I buy Colkhisin?
You can request a quote for Colkhisin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Colkhisin?
Yes, KEHONG BIO provides custom synthesis services for Colkhisin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.